Relationship between tumor grade and HER-2???

My tumor was graded II/III and my HER-2 FISH result was "amplified, 2.2."

After reading some posts, I wondered if there's a correlation between the two, whether they're the same thing but in less detail or what. I know that grade speaks to aggressiveness and general cancer cell characteristics and HER-2 is a particular gene that controls a particular cell receptor that instructs the cell to reproduce (if I got that right--if not, someone please correct me as I want to know this stuff).

Does anyone know the specific differences between the two, assuming they are different?

Thanks!