I was shocked to read an abstract in Tuesday, March 2nd BCN News that stated that the response rate to Herceptin for Her2 patients was only 30%. Based on the good results I've read on this message board, I had assumed that the response rate was much higher.
Here is a bit of the ABSTRACT: Development of Herceptin resistance in breast cancer
cells
[03/02/2004; Cytometry]
Background: Herceptin, a humanized antibody to HER-2, is now utilized
in the clinic for metastatic breast cancer treatment. The response
rate for HER-2+ patients is only 30% and little is known as to
mechanisms of resistance. The mechanism of Herceptin action is
also unknown but has been related to cell cycle inhibition.
The full article can be read at:
http://www3.interscience.wiley.com/cgi-bin...74/ABSTRACT
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