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Old 06-03-2012, 05:01 PM   #4
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Re: Dizziness Question

I'm impressed she can jump out of a low beach chair! I practically need a crane to get me out.

Seriously, I would encourage you to get this checked out. Most people use a two week rulr - if a new symptom persists for two weeks check it out.

Not to scare you, but you are probably aware that her2+ cancer likes to go to the brain, so my oncologist has a super low threshold for any neurological symptoms. An MRI would rule out any issues, and would probably not be a normal part of her upcoming scans.

It's probably nothing, or jumping up and down too much. Tykerb is somewhat protective of the brain anyway as it is a small molecule that crosses the blood brain barrier, which herceptin does not.

Nevertheless, you do want to be vigilant as brain mets, scary as they are, are also treatable especially when caught early.
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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