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Need help! Calling brains in.
Hello Friends. As you know I had the met in my liver taken out by laparoscopy. Well I just got the pathology results:
It is now HER2+++ but ER 20% and PR 0%! I was HER2+++ and ER 90% and PR 20%.The grade is 3 SBR!
My onc said he wanted me on herceptin and tykerb right away. Before I could even think he got me a doctor who put a port in again this afternoon. It was painful. Then his idea is to add chemo and he came up with this strange idea of CMF. A very old chemo isn't it that never worked for HER2s? Am I wrong? Or he also spoke about taxotere. But he said we had time to think of that since I would start chemo in January.
I am starting Herceptin and Tykerb next week.
What do you think of all this?
What a change in the pathology! Have your mets analyzed!
I agree to start H and T because now that I am weakly ER+ maybe it will work better than during the neoadjuvant period.
But why start a toxic chemo since we cannot even measure how it works since right now, I have no other visible tumor. Shouldn t I keep this as an extra weapon and not use it right away or is it better to try to wipe out any new met even invisible since the characterstics of the liver met are so aggressive?
I am down and depressed. I have been crying for 2 weeks now. I don't have hormonotherapy to fight with anymore.
I also had a brain MRI that was clear.
Michka
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08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex
12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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