32 year old w/ HER2+++/Mitral Valve Prolapse & Herceptin???

[jellybean]

Sounds like a great plan. You might consider a liver biopsy before chemo begins. That way you would have an idea of what is in the liver. Otherwise, if it goes away with chemo you might never know.

I had what appeared to be mets in the liver when I was first diagnosed. We did not biopsy them because I had widespread metastases so the biopsy would not change the treatment and we needed to start on chemo ASAP. Well, I had a complete response to the chemo, and to this day my oncologist wonders what the results of a liver biopsy would have been. For her (and me), it is just a matter of intellectual curiosity. For your wife, however, it could have treatment ramifications. For example, if in the unlikely event it is a metastasis, she probably should remain on the Herceptin after the completion of her chemo.

I am not a doctor or a medical professional. Just my two cents.