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Old 07-18-2010, 09:38 AM   #21
AlaskaAngel
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Join Date: Sep 2005
Location: Alaska
Posts: 2,018
Question Re: now they are moving in on how/why of weight gain during chemotherapy 4 breast can

Hi Chelee,

WARNING: My "theory" is NOT fact about this... just simple observation....but my "guess" is that younger patients tend to be less hormone receptor positive, and their metabolism is not slowed down, and maybe that means the cancer cells are also not slowed down as much, and they tend to have more recurrence from that, whereas older patients tend to be more hormone receptor positive (and get more benefit from hormonal treatment) but they recur farther out because their metabolism is slowed down almost to a stop so they are gaining weight and the fat they gain is increasing the inflammation that encourages cancer, and the cancer is feeding off the food they continue to take in at the same level they did before their metabolism slowed down.

I wonder if the others who posted about losing weight (or not gaining any) also were young at time of dx and tx and possibly not very HR+. (Young being under the age of 55.)

A.A.
__________________
Dx 2002 age 51
bc for granny, aunt, cousin, sister, mother.
ER+/PR+/HER2+++, grade 3
IDC 1.9 cm, some DCIS, Stage 1, Grade 3
Lumpectomy, CAFx6 (no blood boosters), IMRT rads, 1 3/4 yr tamoxifen
Rads necrosis
BRCA 1 & 2 negative
Trials: Early detection OVCA; 2004 low-dose testosterone for bc survivors
Diet: Primarily vegetarian organic; metformin (no diabetes), vitamin D3
Exercise: 7 days a week, 1 hr/day
No trastuzumab, no taxane, no AI
NED
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