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Only "slight" decrease on PET....is it time
to change chemo combo or give it more time? I started on Herceptin/Zometa the last wk of Sept. but as most of you know couldn't add chemo until I had my femur surgery & recovered. But now it's been two months since we added the Navelbine and I see there is "only" a slight decrease in axilla area. The mild activity that was seen on liver is now gone...so that's good. Also mentioned is shotty cervical lymph nodes slightly increased. (That WASN'T even mentioned on my last PET/CT...so I don't know where that came from?) Why wasn't it on my last pet report?
I also see that there is an "increase" sclerosis of the left ilium which may be progression? I was hoping it would knock down any bone mets too.
So how much time is usually given to see a good response? I was hoping to stay on this Navelbine/Herceptin/Zometa combo for a while since it's easier to tolerate then others. It did show improvement in axilla and liver...but it's up in the air about two areas of bone mets?
Am I expecting too much for 2 months of Navelbine combo...or should I give it more time? I don't know what the normal time frame is before switching to something else? I see my onc Monday to sort thur this...but rather hear from my Her2 sisters that have been thru this. I want to be prepared for my appt with her! (My Tumor markers dropped with this combo also.)
Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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