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Old 11-04-2009, 01:49 PM   #1
Rich66
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Join Date: Feb 2008
Location: South East Wisconsin
Posts: 3,431
Reminder: Er- can turn pos after Herceptin

Just a reminder to those considered ER- before Herceptin. It may have changed your status and given you more options:

Italian investigators gave trastuzumab to 10 patients with HER2-positive, ER-negative breast cancer. Three of the 10 subsequently had upregulation of ER±, and two of the three were treated with letrozole monotherapy and remained progression free for as long as three years
More:
http://her2support.org/vbulletin/showthread.php?t=38998
And recurrence/mets alone can change it too.

And..Tamoxifen can work on both ER+ and - as well as synergize with chemos. Tamoxifen might be useful if no way to check status.
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