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Old 10-09-2009, 12:50 AM   #1
Lien
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Join Date: May 2006
Location: Haarlem, the Netherlands
Posts: 835
Question prolonged use of aromatase inhibitors after 5 years

Hi all,

Over the next couple of months I'm going to have to make up my mind about continuing on an AI, after 5 years.

I'm trying to make a pro's and con's list. Could you help me add to it?

Pro:
A sense of "doing something" to keep breastcancer away
Possible protection against recurrence
I don't have problems with side effects, they are mild
I forgot my Zoladex shot in June and my periods haven't returned, so I'm probably post-menopausal anyway (just had a bloodtest today)

Con:
Oestrogen may protect me against heart disease and other ailments
No More Pills
There's a chance that AI's may upregulate the Her2 pathway
We don't know about the long term effects yet

Any other reasons why I should or shouldn't?
Any references or new research I should read?

Thanks for your help

Love

Jacqueline
__________________
Diagnosed age 44, January 2004, 0.7 cm IDC & DCIS. Stage 1, grade 3, ER/PR pos. HER2 pos. clear margins, no nodes. SNB. 35 rads. On Zoladex and Armidex since Dec. 2004. Stopped Zoladex/Arimidex sept 2009 Still taking mistletoe shots (CAM therapy) Doing fine.
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