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Old 06-25-2009, 05:41 PM   #1
Cal-Gal
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Join Date: Jun 2009
Location: Los Angeles, CA
Posts: 309
Pathology questions?

Hello Ladies and Gentleman,

I am still learning on this journey--and while I am done with my chemo regiment--I still have questions regarding my surgical path report.

What do the following notations on my pathology refer to?

1.) "Intermediate for Lymphovascular invasion"-it notes that D2-40 immuno stain examined--when I looked and found that--(I think in the lymph node biopsy noted area.) It noted this;
"equivocal, foci suspicious for lymhovascular invasion not present on stain." I was rated negative or 0/1 node. And what are foci??

2.) Ki-67 20%?

3.) SPR(tubule,nuclear, mitotic) Score 8/9 on 3 tumors 7/9 on the other?

I found through reading etc. that #1 refers to the spread of cells into the bloodstream--not sure if that is correct or not? and that is usually reported as positive or negative? mine is intermediate?

I found through reading that #2 and #3 refer to a metric to score the rate at which a tumor is growing?--but I could not find what the actual scores or numbers really mean.

I would appreciate any of you that have any feedback or explanations for me.

I remain high on life today---and grateful for all of you---


__________________
DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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