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Old 11-03-2007, 12:39 PM   #14
AlaskaAngel
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Join Date: Sep 2005
Location: Alaska
Posts: 2,018
timing of use of anti-inflammatories

I found an article discussing a different vaccine, but talking in general about the general same ideas. It doesn't answer the question I have about inflammation from vaccination possibly might not be such a good idea for those who have had bc, but it does address the question about whether being immunized could be a wasted effort if you take anti-inflammatories at the wrong time to discourage the resulting inflammation. I thought the comment attributed to Dr. Phipps was worth sharing. (You can also bring up the article by using "COX2" and "vaccination", if you don't want to sign into medscape, and then choosing COX2 Inhibition Reduces Immunogenicity of HPV Vaccine"):

http://canadiancpd.medscape.com/viewarticle/549869

According to Dr. Phipps, "further research is needed to determine how the timing and dosage of NSAIDs affects the antibody response to vaccination." Until then, he believes it is probably prudent to refrain from NSAID use for at least a week or two before and after receiving a vaccine.

J Immunol 2006


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