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Chemo Dosage Reduced
I've been on Taxol, Carboplatin combo with 3 weeks on and 1 week off; Also Herceptin weekly since July. My blood counts (red, white and platlets) have been dropping severly and I've had to miss 3 treatments due to low counts. Thursday I went for treatment and saw my oncologist as well. Her feeling is that the Carboplatin is what is playing havoc with my blood counts. Her recommendation was that we either reduce the dosage of Carboplatin or cut it out completely since I've been having such a good response to treatment. My last scan showed great improvement in the lung nodules and the brain MRI was clear. I wasn't ready to cut out the carboplatin completly since it does pass through the brain blood barrier. What we decided to do was go with the lower dosage of Carboplatin and keep the Taxol the same. My Carboplatin is now 150mg. Hopefully this will help my counts and also help me have a better quality of life. I will have my next scans in January.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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