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Old 10-23-2007, 09:35 AM   #1
Cathya
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Join Date: Sep 2005
Location: Ontario, Canada
Posts: 752
Could stroke be related to herceptin treatment??

Hi all;

I haven’t posted in quite a while but have enjoyed lurking. I am still NED but undergoing tests (contrast CT’s mostly now) every two months as my onc thinks I might have a hidden tumor (??). I think his concern is my rising tumor markers…..particularly the Serum Her2. It dropped slightly a couple of months ago after being on a rising trend the past two tests and so he is holding off herceptin until he gets the results of the one I just had done yesterday. Problem is that twice before my heart function has dropped on herceptin and I’ve had to stop its use so he really wants to be sure it’s absolutely necessary. I’ve had a couple of MRI’s and some time between the one in February and the one in May I had a stroke!! What a surprise. If I had symptoms I am not aware but he sent me off to see a neurologist last month who ran some tests and I will be getting his report on Friday. I haven’t had high blood pressure but am overweight…..sigh….a constant struggle. The one test looked was an ultrasound of my neck. The neurologist wondered if my radiation treatment of my supraclavicular node tumor had damaged the area but the technologist said I was very lucky and everything seemed clear….also no sign of tumors….Yes!! I wonder if this stroke is related to herceptin in any way?? I hadn't been taking it for about 6 months. I wonder if there’s any other treatment like herceptin available for me….without the heart impact? I have been feeling pretty low over the last couple of months but am feeling better now.
Best regards,
Cathy
__________________
Cathy

Diagnosed Oct. 2004 3 cm ductal, lumpectomy Nov. 2004
Diagnosed Jan. 2005 tumor in supraclavicular node
Stage 3c, Grade 3, ER/PR+, Her2++
4 AC, 4 Taxol, Radiation, Arimidex, Actonel
Herceptin for 9 months until Muga dropped and heart enlarged
Restarting herceptin weekly after 4 months off
Stopped herceptin after four weekly treatments....score dropped to 41
Finished 6 years Arimidex
May 2015 diagnosed with ovarian cancer
Stage 1C
started 6 treatments of carboplatin/taxol
Genetic testing show BRCA1 VUS
Nice! My hair came back really curly. Hope it lasts lol. Well it didn't but I liked it so I'm now a perm lady
29 March 2018 Lung biopsy following chest CT showing tumours in pleura of left lung, waiting for results to the question bc or ovarian
April 20, 2018 BC mets confirmed, ER/PR+ now Her2-
Questions about the possibility of ovarian spread and mets to bones so will be tested and monitored for these.
To begin new drug Palbociclib (Ibrance) along with Letrozole May, 2018.
Genetic testing of ovarian tumour and this new lung met will take months.
To see geneticist to be retested for BRCA this week....still BRCA VUS
CA125 has declined from 359 to 12 as of Aug.23/18


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