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Old 06-23-2007, 02:29 AM   #1
fullofbeans
Senior Member
 
Join Date: Jan 2007
Location: UK
Posts: 617
If you starved cancer of glucose..

how long would it take for the cancer cells to die?

Ok I know it might be a silly question. But I am wondering, if one was to fast (or go on an Atkins diet, I would definitly not advise this) would it starve off the cancer cells since cancer cells can only use glucose and since cancer is glucose greedy and require a lot of it, would it not die off after a reasonably short time? it seems so simple but conceptually quite sound..

There are some research being carried out and clinical trial researching this 'cancer buster' path for example by interfering with glycolysis:
http://www.thresholdpharm.com/sec/pipe_2deoxyglucose

http://cancerres.aacrjournals.org/cg...ull/62/14/3909


Research is quite clear that elevated blood glucose is cancer factor as we all already know

http://www.ncbi.nlm.nih.gov/sites/en...=pubmed_docsum

I noticed that a lot of the supplement indicated for cancer (e.g. Reishi mushroom)have a tendency to reduce blood glucose

Any feedback on fasting/ breast cancer very welcome but for everyone the following is well worth reading;
http://faculty.washington.edu/ely/JOM1.html

Extract:"
Aggressive Glycemic Control in Humans and Animals

This simple Glucose Ascorbate Antagonism theory gives rise naturally to "Aggressive Glycemic Control" (AGC) as a modality that, properly used, appears to have much value against the disorders named above. The main features were: (1) planned ³primitive diet² with reduction of caloric intake (and minimizing refined carbohydrate, rCHO); (2) ascorbic acid (40 milligrams/kg or more, tid); and (3) planned increase in exercise to bring blood glucose into the 75 mg% range (or as low as possible without stress). In 1978 and 1979, two stage-4 breast cancer patients with large tumor burdens, worsening rapidly ("one month" prognoses) although already on chemotherapy, elected to use AGC and both became tumor free in six months (reaching normal weight by losing 40 and 60 pounds respectively) and were still alive in 1992. At least three other humans have been observed to experience rapid tumor-free recoveries from advanced cancer while undergoing insulin-coma therapy, originally planned for their psychoses (Koroljow 1962; and pvt. commun.). An American Cancer Society Institutional Research Committee (at Fred Hutchinson Cancer Research Center and the University of Washington) approved AGC as a research topic in 1983. We were able to reproduce the human result strikingly in an animal model showing strong glycemic modulation of tumor tolerance (Santisteban 1985). The very significantly different (p<.005) mortalities in three groups of mice, 70 days after injection with an aggressive mammary tumor, were: (1) 16 of 24 (slightly) hyperglycemic mice (GHb 5.36); 8 of 24 normoglycemic (GHb 4.67); and (3) only 2 of 20 hypoglycemic (GHb 3.69)."


Many thanks for your comments
__________________

35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies

Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..

superior vena cava blocked: stent but face remains puffy

April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.

Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.



'Under no circumstances should you lose hope..' Dalai Lama
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