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Old 04-21-2007, 09:19 AM   #1
Cathya
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Join Date: Sep 2005
Location: Ontario, Canada
Posts: 752
Dr. Slamon in Canada discusses "cure"

I want to say hi as I haven't been posting in a while. I am doing well and am praying for all of you!!

I just read the National Post this morning....an article by Libby Znaimer who also has breast cancer (although not Her2+). Apparently Dr. Slamon was in Toronto this week to pick up the Gairdner International Award for Medical Research.

In his speach, according to her article, he said, "I don't have the data yet, but I bet you we can improve the cure rates by about one-third with Herceptin." He discussed herceptin being what he calls a "targeted therapy". It attacks the specific genetic mutation that causes the disease. (He said that Her2+ is caused by a mistake in the gene, but it's not hereditary. It just happens when the cell replicates; no one knows why) That's completely different from chemotherapy, which attacks your entire system in the hope that it will kill cancer cells too. "The ultimate goal would be to get rid of chemotheraphy. If we can identify what's broken, we won't throw in these non-specific bombs."

One of the attendees commented to Libby that she would love to go and hug him (wouldn't we all!!). She has two herceptin treatments left. Libby said that Dr. Slamon will consider her cured if she survives for six or seven years. "Cure" is not a word he uses lightly. "I think it sets expectations inappropriately,: he says, "but if you identify what's broken, and you treat it effectivel, it isn't just turning the cancer into a chronic disease. You should be able to eradicate the disease."

God bless you all,

Cathy
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Cathy

Diagnosed Oct. 2004 3 cm ductal, lumpectomy Nov. 2004
Diagnosed Jan. 2005 tumor in supraclavicular node
Stage 3c, Grade 3, ER/PR+, Her2++
4 AC, 4 Taxol, Radiation, Arimidex, Actonel
Herceptin for 9 months until Muga dropped and heart enlarged
Restarting herceptin weekly after 4 months off
Stopped herceptin after four weekly treatments....score dropped to 41
Finished 6 years Arimidex
May 2015 diagnosed with ovarian cancer
Stage 1C
started 6 treatments of carboplatin/taxol
Genetic testing show BRCA1 VUS
Nice! My hair came back really curly. Hope it lasts lol. Well it didn't but I liked it so I'm now a perm lady
29 March 2018 Lung biopsy following chest CT showing tumours in pleura of left lung, waiting for results to the question bc or ovarian
April 20, 2018 BC mets confirmed, ER/PR+ now Her2-
Questions about the possibility of ovarian spread and mets to bones so will be tested and monitored for these.
To begin new drug Palbociclib (Ibrance) along with Letrozole May, 2018.
Genetic testing of ovarian tumour and this new lung met will take months.
To see geneticist to be retested for BRCA this week....still BRCA VUS
CA125 has declined from 359 to 12 as of Aug.23/18


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