Help! Stage 4--Liver Mets

[casabaum]

I am writing on behalf of my sister, a 41 year old female with metastatic breast cancer to both the liver and the bone.<o =""></o>

<o =""></o>My sister has rising tumor markers (CA27-29: 571), a rising bilirubin number (1.7),<o =""></o>
ALT and AST that are rising, but in the area of 180. She has tried a lot of chemo, most recently, Doxil.

Thanks to some links from this site, I found two options.Her last 3 chemo/biological treatments have done little to nothing to stop porgression and I am therefore looking at procedures directed at the liver tumors.

1) LIIT-Laser Induced Interstital Thermotherapy
2) Sirtex Microspheres

I am starting my search now to find hoospitals that might do these procedures. She lives in Dallas Texas and the closer to her the bbetter

If anyone knows of places that offer these procedures or other treatments I should be looking at, please respond.

I have lurked this sight for years, but nevber posted.

Below is a list of some of her other treatments.

Othe treatments:<o =""></o><o =""></o>

Navilbene Carboplatinum Herceptin 11/06-12/06<o =""></o>

Carbo Abraxane Avastin Herceptin 8/06-10/06<o =""></o>

Lapatininb trial (not the Xaloda arm) 6/06-8/06<o =""></o>

Avastin Herceptin carbo 3/06-6/06
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carbo herceptin 9/05-12/05<o =""></o>

Thank you,

Colleen