I Have A Question -

[IRENE FROM TAMPA]

I have been on the Tykerb/Xeloda trial since August/2006.

I have the normal side effects of loose bowels and hand/foot from the Xeloda.

A couple of months ago I started experiencing a lot of dryness in my nose and the worst is my eyes are extremely dry. So much so that it is now affecting my job. I have lots of blurring when I try to read something, especially at work which I assume that all of the florescent lighting does not help.

I had my eye doctor check my eyes and he says I actually have flaking on my eye balls from the severe dryness.

I was thinking that all of this is from the Xeloda but now am wondering if maybe its coming from the Tykerb. I never had the nose/ eye thing before when I took Xeloda.

Has anyone on this trial experienced any of this. I am really getting very fustrated with the eye thing. I can cope with everything else but the vision problem is really irritating. I am on all kinds of eye drops and my eye doctor has suggested maybe plugging my tear ducts to see if that helps. I have added a glare screen to my computer, put a lamp on my desk, had my boss taken out some of the flourescent lights over my head, all to no avail.

Just wondered if anyone has had this problem and what you did.

Thanks