01-06-2007, 07:26 AM
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#1
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Senior Member
Join Date: Nov 2005
Location: Hilton Head Island, SC
Posts: 279
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Tykerb; Is this good news?
I run a google search on BC and had this come up today...
http://www.topcancernews.com/news/46...-breast-cancer
Quote:
The trial, led by Charles E. Geyer, M.D., of Allegheny General Hospital, Pittsburgh and published in the December 28 issue of The New England Journal of Medicine, focused on 324 women whose breast cancer had spread to other organs. The women had already been treated with Herceptin for a median of 42-44 weeks -- and then half received Xeloda chemotherapy and half received both Xeloda and Tykerb.
Women who received the drug combination had more than a 50 percent delay in disease progression. Their cancer spread after a median 8.4 months, compared to 4.4 months for women who received only Xeloda.
Targeted drugs Herceptin and Tykerb are major advances in the fight against breast cancer -- for the 20 percent of diagnosed women with the aggressive HER2 positive disease -- and they are also quite expensive. While some say they are worth every penny if they offer a cure, others question the cost if they only delay the disease progression for a few months. Such was the case in this study.
Perhaps the greatest potential for these agents is for use before breast cancer spreads, when they may improve the chance for a cure.
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me again... I thought a few of the girls here on this site had good response to Tykerb? I think that was with mets right? I know I shouldn't believe all of what I read though.
I am just really hopeful that this is another great breakthrough especially for brain mets, since it crosses over the BBB.
__________________
Kim
Diagnosed 7/05
Stage 3a er+(45%) pr+(68%) Her2+ (40%)
3.8 cm + .8cm multi focal - pleomorphic lobular tumors
high grade DCIS
7/20 nodes
BRCA 2 positive as of 5/07
surgeries: double mastectomy, hysterectomy (LAVH)
A/C,Herceptin for 1 year completed 11/06
femara
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