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Old 11-12-2006, 08:40 PM   #1
Val Pfeiffer
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Join Date: Feb 2005
Location: Wisconsin
Posts: 159
Types of chemo tx, neo-adj vs. adj. etc

I was surfing around this site tonight and I happened to read Kate's signature line -- many of us list the facts about our case, and Kate had listed her neo-adjuvant chemo, which was 4 A/C and 4 taxatore, and this was her treatment very recently, one year after my treatment regime.

Here is my question: what is considered the "gold standard" with regard to chemo tx for Her2+++ breast cancer? When I received the combination of Taxol, Carboplatin and Herceptin for three months prior to my mastectomy and the same drugs for three months after surgery, it was my understanding that was the best approach for this type of cancer. Yet women are still getting A/C and Taxatore. Does anyone know why this is the case? Maybe I was misinformed in December 2004 when I started my treatment.

I find the differences in treatment approaches frustrating at times; I met a woman who had a very similar case as mine, and her oncologist practices in the same group as mine does. Yet she had surgery first, rather than three months of neoadjuvent chemo, which produced such dramatic results in my case.

This certainly isn't an urgent question, but since recurrence is so likely in Her2 cases, I want to get this answer...someday I may need it!

Val
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BLOG:
http://valleygirlvnp.blogspot.com/
Dx 11/04, Age 42, ER-/PR-, HER2+++
3 months weekly Herceptin, Taxol. Carboplatin
Significant tumor shrinkage
Mastectomy 3/05; Stage 3b, 9 cm tumor, 5/8+ nodes
3 more months weekly Herceptin, Taxol. Carboplatin
7/05 30 radiation treatments, IMRT planning approach
Started 1 year of Herceptin 9/05
9/06 Began quarterly triple doses Herceptin. Brain & breast MRIs semi annually.
* * * * * * * * * * * * * * * * * * * * * * * * * * *

6/08 Right breast, intraductal carcinoma, high nuclear grade associated with comedo necrosis; extensive diffusely involved the entire biopy specimen. ER+, PR-, Her2 unknown at this point, 07/08 mastectomy.
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