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Cardiotoxicity after A/C, ? Herceptin
Hello, Everyone,
I found this site recently while doing some research on HER2. Because I believe there are no "coincidences" in life, I have to believe that I am here because of a divine purpose. Thus being said, I would like to do a little brain-storming if I may.
I was diagnosed in late 2002 with Stage IIB, ER/PR+, HER2+, Grade III, node positive BC. I opted for a lumpectomy and had 4 rounds of A/C, followed by 12 weeks of Taxol and 37 radiation treatments. Being part of the clinical study that evaluated Herceptin, I was and am still eligible to receive Herceptin.
Several months after my chemo ended I received a call from my oncologist informing me that my most recent echocardiogram indicated that my ejection fraction had reduced from 65% to 50% from the A/C. Subsequently, it returned almost to the pre-treatment level when last checked.
Because of the risk of cardiotoxicity from the Herceptin, my oncologist and I discussed the issue at length and I decided not to take the Herceptin because of that risk. Now I am having second thoughts about my decision.
Has anyone out there experienced cardiotoxicity from the A/C and then successfully received Herceptin?
I would appreciate any and all comments regarding this issue.
Betsy
Adrian, MI
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