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Has anyone NOT had success w/ herceptin?
I am new here, but not new to bc. I was originally dx in May 2003 at age 23 with IDC. Er/pr- and Her2+++. In Aug 2004 I was dx w/ multiple lung mets in my right lung. I started herceptin and navelbine. My tumor markers (ca27-29) continued to rise, so we tried Xeloda and herceptin in Nov., then taxol/taxotere, gemzar and herceptin for Dec and Jan. In Feb I had my lung drained and started Adria,cytoxan and Avastin, stopping the herceptin. My counts dropped significantly and continued dropping until April. In May I switched to doxil and avastin, only did 2 of those. In June I had scans done and found out that I now had 2 spots in my left lung. So switched to cisplatin and vp16 for 3 days every 3 weeks. Did that once and it made me really nauseous, so then did carboplatin and vp16 for 3 days every 3 weeks until Aug. Had scans done in Aug and I had been stable since the June scans. Went back to cisplatin and did that a few times by itself just one day once a week. My counts dropped really low, so had to get blood in Aug. Two weeks ago I had another blood transfusion and we went back to cisplatin and vp16 over 3 days. I feel really good right now, it didn't make me nauseous and I am no longer having lower back pain like I did beginning in May I think. I go in friday to see my onc and was wondering if I should ask about trying herceptin again. I was thinking maybe it will help now that I am taking a chemo combo that seems to be more effective? Is it possible that I was her2+++ in 03, but not when it recurred? I can't find if it was retested in my notes, but I think it was and was her2+ or else my onc wouldn't have recommended the herceptin in the first place. Right? I know that I went into a lot of detail, but I think that you all are probably the most knowledgable about herceptin compared to other bc sites and the most likely to be able to help me. Thanks in advance.
Blue
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