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brain metastases leptomeningeal
My friend Beatriz – also member of this group – started IT Herceptin with Methotrexate mid-October this year (via Omayya reservoir). Since Dec 2010, she had two gamma-knife treatments (after surgery and whole-brain radiation) and has done therapies with Tykerb/Lapatinib, Xeloda and Neratinib.
Last week the brain MRI showed progression. Some lesions compatible with leptomeningeal metastases have increased significantly. One of the ventricles has collapsed and the Omayya reservoir is not working anymore.
She will now get IV Herceptin with Doxil and they will also administer IT Herceptin via a new Omayya reservoir to be placed in her spine.
If anyone knows of other treatment options, we would be very grateful for information.
thanks!
Frank
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