Please give me some suggestions

[Julie2]

I am on Navelbine for the fourth time in 3 years for mets in mediastinal nodes. Every time I used it only for 3 cycles and stopped as I reached NED with it. Whenever I reached NED I stopped Navelbine and took Tykerb with Herceptin till I had progression(usually it lasted only for 6 months).

This time I finished 4 weeks of Navelbine and it doesn't seem to work because my her2 serum levels are going up instead of going down. Her 2 serum is very reliable to me, it is very accurate for me in showing response.
Also I am having severe side effects with Navelbine this time.

I met with my Onc. yesterday and she asked me to stop Navelbine and ordered a scan which is on this Friday .

I was discussing my options with her and the chemo I can take now are: Xeloda, Taxol and Gemzar and TDM1

I have one TDM1 EAP center two hours away from me.

I am interested in TDM1. But my onc says TDM1 is very effective even for advanced disease, why use it now when disease is not life threating, may be we should keep it for later use.
And she suggest for standard treatments like Xeloda, Taxol or Tykerb with Xeloda. But if I want to go for TDM1, she is absolutely OK.

I just need some advice from you good people about the choices and TDM1. Your advices would help me brainstrom and take the right decision.

Thank you very much.
Julie