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Old 01-06-2010, 02:49 PM   #10
SuePen
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Join Date: Nov 2009
Posts: 12
Re: Invasive Lobular Cancer HER2+ve - anyone else?

I found it:

http://jco.ascopubs.org/cgi/content/full/26/35/5823

This is the best definition I can find of pleomorphic:

In recent years, a new variant of lobular carcinoma, known as pleomorphic lobular carcinoma, has been described. The pleomorphic variant shows most of the architectural features of classic lobular carcinoma, but is composed by large and pleomorphic cells. In addition, this variant is reported to have a more aggressive clinical behaviour when compared to its classic counterpart. In fact, the behaviour of the pleomorphic variant is more similar to that of high grade ductal rather than lobular carcinomas.

I don't yet know if mine was pleomorphic hopefully I'll find out.

Sue
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