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Hi Cathy,
I had the same reaction with Zometa exactly one year ago. I had it late Thursday afternoon. I went to school early Friday morning and by 9:30 I had to leave because I was in such pain. This is coming from someone who only missed 4 days of teaching the year I had AC followed by Taxol. I also was back at school one week after brain surgery a year ago. I normally have to be quite sick to stay home. I ended up staying in bed Friday, Saturday, and Sunday after that first Zometa infusion.
Later, each infusion became somewhat easier and I learned to take Advil right away. Now, I don't have to take anything, I have no pain, and my body has adjusted to it. I have been told that it helps to have a longer infusion. Good luck! I think that if you continue with it you will find that your body will adjust. It also helps to take a warm bath for the pain.
Best regards,
Barbara H.
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