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		|  11-06-2007, 06:18 AM | #1 |  
	| Senior Member 
				 
				Join Date: Aug 2003 Location: Morris, IL 
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				HAPPY 4th ANNIVERSARY BRENDA H
			 
 Wanted to be the First to Congratulate you on 4 years...November 7th...WHOOOOPPEEEEEEEEE....many many more for you!!!! Wanted to do this before I forgot and just in case you decided to get rowdy tomorrow and now show up on the board...we know how you Texas Gals Are!!!!!What a great milestone, and each one gets sweeter! Seems this day is as important as our birthday...
 
				__________________ "Be kinder than necessary, for everyone you meet  is fighting some kind of battle."Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications) 
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant 
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin 
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments 
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression 
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin |  
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		|  11-06-2007, 07:58 AM | #2 |  
	| Senior Member 
				 
				Join Date: Jul 2007 Location: Canada 
					Posts: 2,193
				 
		 
		 
		
		 
		
		
	
		
	
	 | 
				 congrats 
 Congratulations Brenda - I am very happy for you - you are 4 years old !!! 
Hope you have a great celebration; maybe a margarita or a 1/2 beer (stay away from the Coors Light)  
				__________________PinkGirl
Dx Aug/05 at age 51
2cm. Stage 2A, Grade 3
ER+/PR- Her2 +++
Sept 7/05 Mastectomy
4 FAC, 4 Taxol, no radiation
1 year of Herceptin
Tamoxifen for approx. 4 months,
Arimidex for 5 years
 Prophylactic mastectomy June 22/09
" I yam what I yam."  -  Popeye
My Photo Album
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		|  11-06-2007, 08:42 AM | #3 |  
	| Senior Member 
				 
				Join Date: Jan 2007 Location: Thornhill, Ontario
Canada 
					Posts: 2,320
				 
		 
		 
		
		 
		
		
	
		
	
	 | 
 Congrats to you Brenda - 4 years out and now NED!!  Do the happy dance girl.
 all the best
 caya
 
				__________________ER90%+/PR 50%+/HER 2+
 1.7 cm and 1.0 cm.
 Stage 1, grade 2, Node Negative (16 nodes tested)
 MRM Dec.18/06
 3 x FEC, 3 x Taxotere
 Herceptin - every 3 weeks for a year, finished May 8/08
 Tamoxifen - 2 1/2 years
 Femara - Jan. 1, 2010 - July 18, 2012
 BRCA1/BRCA2 Negative
 Dignosed 10/16/06, age 48 , premenopausal
 Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
 Reclast infusion January 2012
 Oopherectomy October 2013
 15 Years NED!!
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		|  11-06-2007, 10:10 AM | #4 |  
	| Senior Member 
				 
				Join Date: Mar 2007 Location: CHARLOTTE NC USA 
Home town (ECUADOR) South America 
					Posts: 542
				 
		 
		 
		
		 
		
		
	
		
	
	 | maravilloso ...congratulations my Dear 
				__________________ Lily Diag April/06 5 months after give birth my son Max  stage IV mets on liver (5 tumors) 38 year old, her2+++ and ER+PR+ from32 nodes 4 positives mastectomy right breast chemo before surgery herceptin/carboplatin/taxotere ,clear and surgery have radiation 20, `& then herceptin and tamoxifen  NED until Aug/07 body only then 'n June 04-06-07 .1 lesion of 1.6 cm on cerebellum ...novalis ,open sugery  5m.m brain met again novalis, 4mm.In the liver. Waiting 2 months now 3 tumors enroll on T-MCC trial start first infusion Nov 5/07 at Dec 17 scan show one tumor despair the 2nd and 3th diminish Doc said great results until March/08 ct scan show progression  03-05-08 start tykerb & xeloda |  
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		|  11-06-2007, 10:58 AM | #5 |  
	| Senior Member 
				 
				Join Date: Nov 2005 Location: Northern Calif. 
					Posts: 981
				 
		 
		 
		
		 
		
		
	
		
	
	 | Yay!!! Happy 4 year anniversary!! I wish you many many more happy years ahead!!
 Lexi
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		|  11-06-2007, 11:18 AM | #6 |  
	| Senior Member 
				 
				Join Date: Feb 2006 Location: Acworth, GA 
					Posts: 2,104
				 
		 
		 
		
		 
		
		
	
		
	
	 | Congratulations on your 4 year aniversary.  Quite a mile marker!   Keep up the good work. 
				__________________Kate
 Stage IIIC Diagnosed Oct 25, 2005 (age 58)
 ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
 Neoadjunct chemo: 4 A/C; 4 Taxatore
 Bilateral mastectomy June 8, 2006
 14 of 26 nodes positive
 Herceptin June 22, 2006 - April 20, 2007
 Radiation (X35) July 24-September 11, 2006
 BRCA1/BRCA2 negative
 Stage IV lung mets July 13, 2007 - TCH
 Single brain met - August 6, 2007 -CyberKnife
 Oct 2007 - clear brain MRI and lung mets shrinking.
 March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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		|  11-06-2007, 11:37 AM | #7 |  
	| Senior Member 
				 
				Join Date: Oct 2005 
					Posts: 3,519
				 
		 
		 
		
		 
		
		
	
		
	
	 | Thanks all! And it seems like just yesterday...LOL.
 Happy dance and a margarita sounds like just the ticket. I will clink margarita glasses with ya in S.A. Sheila!
 
				__________________Brenda
 
 NOV 2012 - 9 yr anniversary
 JULY 2012 - 7 yr anniversary stage IV (of 50...)
 
 Nov'03~ dX stage 2B
 Dec'03~ Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
 Jan'04~ Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
 Sept'05~ micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
 Aug'06~ micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
 Feb'07~ Genetic testing, BRCA 1&2 neg
 Apr'07~ MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
 May'07~ Started Tykerb/Xeloda, no WBR for now
 June'07~ MRI  - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
 Aug'07~ MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
 Oct'07~ PET/CT & MRI show NED
 Apr'08~ scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
 Sept'08~ MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
 Oct'08~ dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
 Dec'08~ Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
 June'09~ new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
 Sept'09~ new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
 Oct'09~ 25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
 Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
 June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
 Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
 Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
 Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
 Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.
 
 "I would rather be anecdotally alive than statistically dead."
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		|  11-06-2007, 01:10 PM | #8 |  
	| Senior Member 
				 
				Join Date: Jun 2006 Location: San Antonio, TX 
					Posts: 2,357
				 
		 
		 
		
		 
		
		
	
		
	
	 | What a great day to celebrate!  Congrats and many, many more coming! 
				__________________MA in TX.
 Grateful for each and every day....
 
 Diag. 12/05 at age 60
 Stage II, Grade 3, 4.5 cm primary tumor
 ER/PR- Her2 +3 strongly positive
 Her2 by FISH 7.7 amplified
 vascular invasion
 Ki67 20% borderline
 Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
 April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
 April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
 Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
 Radiation & Herceptin Jan. 22 - March 1, 2007
 Finished Herceptin Dec. 10 '08! One extra year.
 Port removed August, 2012.
 8 1/2 years since diagnosis! 5 1/2 Years NED!
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		|  11-06-2007, 01:10 PM | #9 |  
	| Senior Member 
				 
				Join Date: Aug 2006 Location: Sheboygan, WI 
					Posts: 2,582
				 
		 
		 
		
		 
		
		
	
		
	
	 | Sending a hug to you Brenda.  
 Mary Jo
 
				__________________ "Be still and know that I am God." Psalm 46:10 Dx. 6/24/05 age 45 Right Breast IDC ER/PR. Neg., - Her2+++ RB Mast. - 7/28/05 - 4 cm. tumor Margins clear - 1 microscopic cell 1 sent. node No Vasucular Invasion 4 DD A/C - 4 DD Taxol & Herceptin 1 full year of Herceptin received every 3 weeks 28 rads prophylactic Mast. 3/2/06 17 Years NED <>< Romans 8:28 
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		|  11-07-2007, 12:43 AM | #10 |  
	| Senior Member 
				 
				Join Date: Sep 2006 Location: Houston, Texas 
					Posts: 624
				 
		 
		 
		
		 
		
		
	
		
	
	 | Happy Belated Anniversary, Brenda! |  
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		|  11-07-2007, 01:12 AM | #11 |  
	| Senior Member 
				 
				Join Date: Feb 2006 Location: Southern, CA 
					Posts: 2,511
				 
		 
		 
		
		 
		
		
	
		
	
	 | Brenda, Congratulation to you and your sweetie, "NED". You two make such a great couple. I'm sure glad NED likes to get around...you certainly can't have him all to yourself. Here's to a long happy road with NED by your side. Sending lots of happy thoughts your way.
 Chelee
 
				__________________DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
 Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
 Chemo started 2-7-06 -- TCH - - Finished 6-12-06
 Finished yr of wkly herceptin 3-19-07
 3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
 9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
 9-28-09 Loading dose of Herceptin & started Zometa
 9-29-09 Power Port Placement
 10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
 11-19-09 RT. Femur surgery - Rod placed
 12-7-09 Navelbine added to Herceptin/Zometa.
 3-23-10 Ten days of rads to RT femur. Completed.
 4-05-10 Quit Navelbine--Herceptin/Zometa alone.
 5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
 Results to FISH was unsuccessful--this happens less then 2% of the time.
 7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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		|  11-07-2007, 06:35 AM | #12 |  
	| Senior Member 
				 
				Join Date: May 2007 Location: Northern Michigan 
					Posts: 68
				 
		 
		 
		
		 
		
		
	
		
	
	 | Congratulations on your anniversary Brenda, and many, many more!Love & hugs
 Michelle
 
				__________________Sept. 2003- 5cm tumor in left breast Her2+ Er- Pr- grade 3,
 Mastectomy & 11 nodes removed, all negative.
 4 rounds A/C + 12 wky Taxol
 25 rads
 Dec 2006- recurrence Stage IV (diagnosed 3 days before Christmas!) Lymph nodes in chest, liver, 3 ribs
 January 2007- 3 tri wkly rounds of Taxol/Herceptin
 Response to lymph nodes in chest, but several more bone mets (skull, shoulders, more ribs, femur, several on spine), liver tumors still growing.
 March 2007- 8 wkly rounds of Navelbine/Herceptin/ every 4th wk Zometa
 Lymph nodes in chest look great, but more bone mets (of course!), Clavicles, hips, and sacrum (above tail bone) to add to the list. Liver mets still growing.
 June 5- started Tykerb/Xeloda
 
 Aug 14- Scans are showing great progress! Tumor shrinkage and bones are healing!
 
 Nov 21 CT scan shows tumor growth in liver & bones next Doc appt on 11-27
 
 Dire need of a lot of prayers and a miracle.
 Stay at home mom, 5 yr old girl & 8 yr old boy.
 Wife of loving husband
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		|  11-07-2007, 08:31 AM | #13 |  
	| Senior Member 
				 
				Join Date: Sep 2005 Location: Riverside, CA 
					Posts: 484
				 
		 
		 
		
		 
		
		
	
		
	
	 | Awesome Brenda, we'll keep celebrating for the next 40 years! |  
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		|  11-07-2007, 09:18 AM | #14 |  
	| Senior Member 
				 
				Join Date: Oct 2005 Location: New Jersey 
					Posts: 3,154
				 
		 
		 
		
		 
		
		
	
		
	
	 | Dear Brenda,So happy for you....Love wishing "Happy Anniversary" to you.
 Let's add another 4 to the 4 = 44 more for you.
 
 Hugs,
 Jean
 
				__________________Stage 1, Grade 1, 3/30/05
 Lumpectomy 4/15/05 - 6MM IDC
 Node Neg. (Sentinel node)
 ER+ 90% / PR-, Her2+++ by FISH
 Ki-67 40%
 Arimidex 5/05
 Radiation 32 trt, 5/30/05
 Oncotype DX test 4/17/06, 31% high risk
 TOPO 11 neg. 4/06
 Stopped Arimidex 5/06
 TCH 5/06, 6 treatments
 Herceptin 5/06 - for 1 yr.
 9/06 Completed chemo
 Started Femara Sept. 2006
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		|  11-07-2007, 11:10 AM | #15 |  
	| Senior Member 
				 
				Join Date: Oct 2005 
					Posts: 3,519
				 
		 
		 
		
		 
		
		
	
		
	
	 | I am not a jealous girlfriend - as a matter of fact, I like that NED is a swinger... the more NED cats around with other folks, the happier it makes everyone!! LOL 
				__________________Brenda
 
 NOV 2012 - 9 yr anniversary
 JULY 2012 - 7 yr anniversary stage IV (of 50...)
 
 Nov'03~ dX stage 2B
 Dec'03~ Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
 Jan'04~ Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
 Sept'05~ micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
 Aug'06~ micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
 Feb'07~ Genetic testing, BRCA 1&2 neg
 Apr'07~ MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
 May'07~ Started Tykerb/Xeloda, no WBR for now
 June'07~ MRI  - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
 Aug'07~ MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
 Oct'07~ PET/CT & MRI show NED
 Apr'08~ scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
 Sept'08~ MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
 Oct'08~ dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
 Dec'08~ Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
 June'09~ new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
 Sept'09~ new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
 Oct'09~ 25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
 Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
 June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
 Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
 Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
 Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
 Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.
 
 "I would rather be anecdotally alive than statistically dead."
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		|  11-07-2007, 12:08 PM | #16 |  
	| Senior Member 
				 
				Join Date: Sep 2005 
					Posts: 556
				 
		 
		 
		
		 
		
		
	
		
	
	 | Congratulations Brenda! 
				__________________Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
 Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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