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Old 07-02-2007, 12:28 PM   #1
Grace
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Good news to share!

I've had lots of symptoms of brain mets for some weeks now and had an MRI of the brain in Friday, as well as a stress/echo test--one test in morning and one in afternoon. I haven't yet gotten official results from cardiologist yet, but doctor who ran the test said my EF looked good, they couldn't find the mitral valve prolapse which I was told I had a year ago (so that's good), my very small pericardial effusion (probably caused by herceptin) is very very small (so that's even better), and no apparent blockages.

Oncologist just called to say MRI is clean, except for some small vessel damage (which is from aging). My dizziness, I think, was from my BP going down, so I cut my dosage in half and am doing fine. Nausea, I think, is because my reflux disease is getting worse. But hooray, hooray, it wasn't brain mets.

And then, on Friday, we offered for a house in Maine (our alternate house) as the one we really wanted was stuck in legal issues. Then, just as I got off the telephone with realtor for alternate house, I received an email from realtor for preferred house that it's available and we can close asap. People in Maine are so nice (I'm remembering Sandy too). The second realtor was so understanding when I had to withdraw offer. I think I'll like it there very much.

So it's been a good day all around. I am also finished herceptin on August 9, so we can move to Maine (some ten hours from our place in New York) without having to travel back and forth. My husband Miguel is the most positive person in the world, and I'm such a cynic, but he kept telling me it would be ok, and (this is for you, Andi), I intend to take the positive road from now on. No more cynicism from me (well perhaps I'll give myself one day a month where I can be as cynical as I want).

Thank you all for listening. You are the only group of people who can possible share the sense of relief I had with that phone call. I know how good it makes me feel when I read one of your posts that a test has come back negative, and how much pain I feel when it's been positive.

I was watching "Hannah and Her Sisters" recently by Woody Allen, and the protagonist, who is thinking of suicide, goes to see a Marx Brothers movie and decides that whatever life has to offer (whether an afterlife or not) that the act of living itself is wonderful. And, of course, at the end, he gets the girl and all is well. And it's very very true.
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Old 07-02-2007, 12:54 PM   #2
StephN
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Good feelings!

Dear Grace -
Your post was a good boost for me as I face a new week. As you say, the news on this board can affect us, as we have a well of understanding for each other.
NO evidence of brain mets is a real weight lifter, which enabled you to take other action.
And the news on the preferred house is really excellent. Now you can settle in and have some peace and quiet to dive back in to the next inspector Cenni book.

BTW, I really enjoyed "The Last Enemy" and especially the fact that the story really TAKES you to that part of Italy with place details and Italian phrases tossed in here and there. Art history was one of my "minors" in college, so your story has some particular interest for me. Hope you are finding a way to get Cenni out of the small burg to which he has been relegated. And that some of the characters will resurface in the next books to get their just desserts in some interesting fashion! This book left me wanting more - so get busy! Ha, ha...
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"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.

MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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Old 07-02-2007, 01:18 PM   #3
Grace
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Thanks Steph,

Yes it was a weight, but with my usual diligence I began researching small vessel disease and I now have a new worry! But not that much of a worry. I really do plan to keep my resolution and stay positive.

And thanks for compliments on book. I plan to finish the second by the end of July--I've already written 180 pages, so Alex does get out of the burg (Foligno), back to Perugia, and although not in this book, but in one of them, Artemisia does get hers! Just haven't figured out how yet.

Thanks again.
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Old 07-02-2007, 03:22 PM   #4
Adriana Mangus
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Congrats!

Dear Grace:

My husband, daughter and I visited about 4 years ago (we stayed in Rockport), and loved it. The people are very nice, it's a completely different life style from what we are use to here in California. We went to a couple of Hockey games in Portland (we're fanatics). Visited your hockey town as well right after 9/11. Great Rangers fans you got there.

Wish you the best to yo and your husband, and yes stop being a cynic!! Listen to your husband;sounds like mine, always caring and extremely positive.

I guess you are joining Stephen uh? :-)
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1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--
NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.

2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.

2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
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Old 07-02-2007, 03:30 PM   #5
R.B.
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Grace

I am delighted you had two lots of good news.

RB
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Old 07-03-2007, 10:23 AM   #6
tricia keegan
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Hi Grace, so glad you got good news on your scan and wish you lots of luck health and happiness in your new home
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 07-03-2007, 11:57 AM   #7
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Moving ahead

Maine should be just what the doctor ordered, Grace, and hopefully the source of lots of "character" for future efforts. Glad you are getting good test results!

AlaskaAngel
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Old 07-03-2007, 07:00 PM   #8
Mary Jo
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Hi Grace,

I, too, am delighted that things are going so well all the way around. What a wonderful feeling for you and how relieved you must be. Life is good, isn't it? Even when the not so good things come our way there is incredibly much to be thankful for.

The glass being 1/2 full or 1/2 empty.........................it's so much better when we can see things on a 1/2 full scale, isn't it?

I have joy in my heart for you........................

Mary Jo
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Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

<>< Romans 8:28
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Old 07-06-2007, 04:05 PM   #9
Believe51
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Location: RHODE ISLAND (Ed getting me a latte on 2nd Cancerversary Cruise 2008) 'BELIEVE': To accept as true or real, To have faith in, To presume ALWAYS BELIEVE
Posts: 2,999
Thumbs up Yes!!!!!!!

Yes My Dear Grace, how I needed to hear this news today. Actually any day is great. You have been in our prayers and heart & certainly warmly on our minds. Keep up the good work.

Also, my husband is back from many consults, one being Dana Farber. Although he has many 'salted' brain mets(covered with spots) we are thinking that we can use the whole brain radiation to get rid of most of them & let the Tykerb/Xeloda do the rest.(We have to sound positive, but I really do BELIEVE!!!!) Wish us luck on our new path!

Waiting For A Miracle..>Believe51
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9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI
6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression
10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement,
NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5
12/22/08SpinalMets1/14/09SpinalRads2/17/09BrainMRI=NoNewMets4/20/09BoneScan5/14/09Ixempra6/1/09BrainMRI=NumerousMets6/24/09DFCIw/DrBurstein6/26/09Continue
Ixempra/Faslodex/Zometa~TM now lower7/17/09Stop Ixempra By Choice9/21/09HOSPICE10/16/09Earned His Deserved Wings And Halo=37 Month Fight w/Stage 4 IBC, Her2+++,My Hero!!
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Old 07-10-2007, 05:08 PM   #10
MCS
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Grace,

a wonderful fall colors ahead for you up there.

MCS ( maria)
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Old 07-10-2007, 08:18 PM   #11
Bev
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Glad is well on all fronts. Now my interest in your books is piqued because my ancestors hail from Perugia. BB
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Old 07-10-2007, 09:43 PM   #12
Grace
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Bev,

Really from Perugia! How wonderful. It's rare that you meet people in the U.S. whose family comes from Umbria. I guess they liked it too much to leave home. My detective, Alessandro Cenni, is a commissario in the Perugia Questura, which is near the football stadium if you know Perugia. I hope you've been. It's a wonderful city, with a major university, and one of the great central streets in Italy. And there's a cafe there that has the most wonderful chocolate desserts ever, by name of Sandri. Name of book is: The Last Enemy, Grace Brophy, Soho Crime is the publisher.

And if you're interested Michael Dibdin, one of my favorite writers (just died unfortunately), set his first novel in Perugia, Rat King. But my favorite is Dead Lagoon set in Venice.
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