Hi Linda,
I had several nodes in my neck area that started out about pea sized and got about the size of lima beans over a 3 month period before I started Xeloda. They were "twingey", with tenderness and some sharp pains once in a while. These nodes responded pretty well to Xeloda; after about six months of 500mg twice a day we couldn't feel them anymore and the PET/CT was clear. They remain NED, but I still remain on Xeloda with Herceptin as I just finished radiation for right axilla nodes that didn't respond to the Xeloda but have to the rads. Waiting a month or so to do scans and hope for another "all clear".
Hope this helps Dear, and keeping my fingers crossed for Tykerb for you
<3 Lolly