Her2 twice as likely to get brain mets Yikes!!!!That is very scary information - we Her2 gals seem cursed - guess we all have to be vigilant, watching for symptoms and at the same time enjoy every blessed day.
Wow, this is scary! We need to take seriously all the advice we've received on this site about checking for brain mets. Does anyone know what symptoms to watch for? Or how often we should have MRI's or PET's or whatever? What does show brain mets best, by the way? This is one time we need to all nag and cajole each other to be vigilant! Hugs, Tricia
Under INDEX on the HOME page you will find a list of items.
Click on METASTATIC BRAIN TUMOR and you will get a whole host of links to all kinds of articles and sites dealing with brain mets.
As for symptoms, there is a long list and what they are may be caused by different areas of the brain affected.
Numbness in the arm or hand
Seeing "stars" or other sudden vision difficulty
Headaches that are worse in the morning and get better during the day
Balance problems - wobbliness
These are some of the main ones.
As for ME - I had NO symptoms. I Just have an annual screening ever since I became metastatic. Some of you gals who are newer on this board did not go through the whole spate of board members who came up with brain mets earlier this year. Maybe do a search and see what they all had to say.
One thing that shocked me was the comment by one lady who is a 25-year survivor and is active with another support group. There she was in San Antonio and told me that it was news to her that the chemos and Herceptin DO NOT cross the blood-brain barrier! How can she support people when she lacks such BASIC knowledge of the workings of these drugs???
Good thing we had those little brains as ice-breakers so that we could "break the news" to some people!!
While in San Antonio, we had lengthy discussions with Dr. Eric Winer of Dana Farber and a few of the neuro-oncologists from GSK. They recognize the problem and are currently working on it.
Dr. Winer is conducting clinical trials using Tykerb which has shown to pass through the blood brain barrier. They both feel confident that they will achieve considerable success in the near future.
Ok, if i got this right they counted only 60 of the 100 women? If thats right and they said 57% of the 60 were Her2 pos. then 43% were Her2 neg, right. Well how the heck did they get "twice as likely to have brain mets from that?" Did i miss something?
Joe, this is why i hope they get the adjuvant Tykerb(lapatinib) trials going. If this drug could PREVENT brain mets from coming in a oral form BRING IT ON!! Are the Glaxo reps seeing this need? I hope they are!!
great
Chack this site for info
Hybrid Mode
