I think it is important to have the serum her-2 pulled with the CA 27/29 or CA 15-3 and the CA 125 and CEA on a regular basis. In my experience, these numbers are the very first to point to something being active. For years, I have them pulled just minutes PRIOR to each herceptin infusion as this allows us to see them at their peak.
It is also a "fun" experiement to take your herceptin, say on a Monday, if you are doing the every 3- week protocol, then pull your markers on each of the consecutive FRIDAY's till you are infused with Herceptin again...fyi. Very telling data...if you have active mets..the numbers will go up a bit or a lot, each Friday until your next Herceptin infusion...when they will drop rapidly, only to start going up, uP, UP again...just keep pushing that boulder up the her-2 hill, folks..smile..
Gina
GPOPP@Comcast.net