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01-19-2007, 04:08 PM
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#1
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Senior Member
Join Date: Sep 2005
Location: Grand Rapids, MI
Posts: 1,516
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Curious...
Who had dose dense and who had every 3 week chemo? Take care and God bless.
Rhonda
__________________
Rhonda
Dx 2/1/05, Stage 1, 0 nodes, Grade 3, ER/PR-, HER2+ (3.16 Fish)
2/7/05, Partial Mastectomy
5/18/05 Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan)
8/1/05 Finished 33 rads
8/18/05 Started Herceptin, every 3 weeks for a year (last one 8/10/06)
2/1/13...8 year Cancerversary and I am "perfect" (at least where cancer is concerned;)
" And in the end, it's not the years in your life that count. It's the life in your years."- Abraham Lincoln
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01-19-2007, 04:13 PM
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#2
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Senior Member
Join Date: Nov 2004
Location: Colorado
Posts: 131
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Dose dense...
Lisa was weekly herceptin for 3 weeks, then off for 1 week. 3 years, until tykerb trial.
Love and Light
Mel
__________________
Mel Gordon, Husband of Lisa Lowe - Queen of Love and Light and the bravest person I know!
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01-19-2007, 04:28 PM
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#3
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Senior Member
Join Date: Nov 2004
Location: Streetsboro, Ohio
Posts: 365
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Three years ago I had taxol, carboplatin, and herceptin 3 weeks on and one off. I was given a smaller dose then the once every three week schedule. This worked well to bring tumor markers down and keep active bone mets stable. I also had zometa monthly for bone mets.
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01-19-2007, 04:49 PM
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#4
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Senior Member
Join Date: Sep 2005
Posts: 161
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I did dose dense (every 2 weeks) because my best friend was getting married on her birthday after "dating" the guy for 24 years!!! I had to get to Las Vegas in time to be the matron of honor....bald tho I was.....
__________________
Diag. Oct. 2004 age 54 left breast
Stage 1 grade 3; 6mm IDC; unknown amount of DCIS
with comedo necrosis; node neg.
Nottingham Grade 7/9
ER 91% PR 62%; Her2 3.6 by ICH; KI-67 35%
Nov 2004 Lumpectomy; SNB failed so had
full axillary clearance;
Dec 2004 2nd lumpy for clean DCIS margins.
Jan/Feb 2005 4 A/C dose dense;
33 rads finished 6/2005;
Began 5 years Arimidex in 6/2005
No Herceptin
9/2007 Quit Arimidex due to severe side effects.
NED
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01-19-2007, 05:37 PM
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#5
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Senior Member
Join Date: Sep 2005
Posts: 232
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I did dose dense AC & T.
Karen
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01-19-2007, 05:45 PM
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#6
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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I had dense dose AC followed by Taxol.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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01-19-2007, 08:11 PM
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#7
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Senior Member
Join Date: Feb 2006
Posts: 1,014
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I did taxotere every 3 weeks, herceptin weekly (still doing that), and had Xeloda 2weeks on/1 week off......................sherryg683
__________________
Sherry
Diagnosed: December , 2005 at age 44
13+ positive lymph nodes
Stage IV , Her2+, 2 small mets to lungsChemo Started: Jan, 2006
4 months Taxotere, Xeloda, Hercepin
NED since April 2006!!
36 Rads to follow with weekly Herceptin indefinately
8 years NED now
Scans every year
Life is not about avoiding the thunderstorms, it's about learning to dance in the rain!
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01-19-2007, 08:18 PM
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#8
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Hi Rhonda,
Did TCH every 3 weeks, Sept completed chemo. Now on herceptin every 3 wks and Femara.
Regards,
Jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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01-19-2007, 08:23 PM
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#9
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Senior Member
Join Date: May 2006
Location: northshore suburb of chicago
Posts: 1,093
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I had A/C every 3 weeks for 12 weeks and I get herceptin every 3 weeks except the first 2 doses were weekly with the first one being a loading dose.
__________________
~Rina~
Dx:3/06 had a lumpectomy April 19, 2006
Her2+ er/pr- Stage I Grade 3 tumor size 1.4 cm, node negative
AC 4 dense doses
34 radiation treatments including booster doses
receiving herceptin every 3 weeks since late August 2006 for 12 months
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01-19-2007, 08:44 PM
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#10
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Senior Member
Join Date: Oct 2005
Posts: 823
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I had AC X 4 Dose Dense, and I had Abraxane X 4 Dose Dense. My Herceptin was done every week for a year.
__________________
Vicki
Texas
Biopsy Dx'd 3-23-05 Age 48
MRM 4-5-05 w/ 2 tumor's 5cm, and 6 cm (right side)
IDC (poorly differentiated infiltrating ductual carcinoma)
5+/16 nodes
Stage III A
Grade 3
ER/PR-, Her2/neu ++
Ki67 78%
Begin Chemo 5-2-05 4XAC Dose Dense , 4X Abraxane Dose Dense (ended August 05)
28 Rad's ended October 13 2005
Started Herceptin Weekly August 2005 for one year
Had a Simple mastectomy left side after Mamo showed incresed micro-calcifications. Jan. 17 2006.
Brain MRI Feb.2006--All Clear
August 28, 2006 Last Weekly Herceptin.
October 2006--Colonoscopy, 6 Polyp's removed--all B9
PET Scan July 2007
Abdominal MRI Oct. 2007---2 Right Kidney Cysts
Core Biopsy-- Lump on Scar Line 1-10-08---B9
Brain MRI 6-2008--All Clear
PET/CT Scan 6-2008
Sept. 8 2008, 4CM area removed from mastectomy scar line. Proved to be B9.
PET/CT Scan-- July 2009 --All clear
August 17,2009 ---Had Port Removed
6 Years NED -- April 5,2011
DX'd with Melanoma left arm 10-10-2011
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01-19-2007, 11:08 PM
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#11
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Senior Member
Join Date: Sep 2005
Location: South Dakota.
Posts: 621
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CEF X 6 once every 3 weeks
__________________
Blessings and Peace,
Barbara
DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy
"at least" 4.5 cm IDC 1+node ER+61% /PR-
Assiciated Intraductual component with Comedo Necrosis
Her2+ FISH8.6 IHC 2+
5 1/2 CEF Arimidex
Celebrex 400mg daily for 13 months
Prophylactic mastectomy
Estradiol #: 13
PTEN positive, "late" Herceptin (26 months after chemo)
Oct 05: Actonel for osteopenia from Arimidex.
May 08: Replaced Actonel with Zometa . Taking every 6
months.
Accepting the gift of life, I give thanks for it and live it in fullness.
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01-23-2007, 02:58 PM
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#12
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Senior Member
Join Date: May 2006
Location: California
Posts: 668
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Herceptin weekly
Hi Sherry: I do herceptin every three weeks, the onc said that it does not matter the frequency, but the dosage does. I see some women on this site that do Herceptin weekly. Have you asked your doctor why weekly as opossed to every three weeks. Also what's the dosage for you/ Is it based on your weight? Thank you.
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.
2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.
2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
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01-23-2007, 03:15 PM
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#13
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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Had both
My first treatment was DD, weekly Adriamycin for 12 weeks. (Believe me - I never thought THAT would end!)
Followed by 4 Taxotere 3 weeks apart.
When treated for mets, it was weekly for 7 months until I reached what looked like (and was) NED.
Then went on the 3 week dose of Herceptin.
Are you compiling a chart, Rhonda??
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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01-24-2007, 07:55 AM
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#14
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Senior Member
Join Date: Sep 2005
Location: Grand Rapids, MI
Posts: 1,516
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Steph...
No, I'm not, just curious. Don't really know what point a chart would be as treatment is ALWAYS changing and what we had is now obsolete. Take care and God bless.
rhonda
__________________
Rhonda
Dx 2/1/05, Stage 1, 0 nodes, Grade 3, ER/PR-, HER2+ (3.16 Fish)
2/7/05, Partial Mastectomy
5/18/05 Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan)
8/1/05 Finished 33 rads
8/18/05 Started Herceptin, every 3 weeks for a year (last one 8/10/06)
2/1/13...8 year Cancerversary and I am "perfect" (at least where cancer is concerned;)
" And in the end, it's not the years in your life that count. It's the life in your years."- Abraham Lincoln
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01-21-2007, 06:55 PM
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#15
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Senior Member
Join Date: Jul 2006
Location: ontario, canada
Posts: 48
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Hi Rhonda,
Starting last March, I had AC chemo every three weeks, although my 3rd and 4th sessions were deferred by one week due to low white counts. Taxol was also every three weeks, with no delays. I am now on Herceptin every three weeks for a year and Tamoxifen daily. My onc didn't even suggest DD therapy, I don't know why. Maybe it just isn't standard treatment here in Canada, as much as it is in the U.S.
__________________
Karen
"The Good Lord gave us mountains, so we could learn how to climb!"
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01-21-2007, 08:36 PM
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#16
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Senior Member
Join Date: Sep 2005
Location: Mountains of Virginia
Posts: 2,267
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I had 4 DD A/C every two weeks then 10 Taxol/Herceptin weekly. Continued Herceptin weekly until after rads. Then switched to herceptin every three weeks (completed 18 mos) and added Arimidex. Zometa added in Dec 06 for osteopenia.
________
Vaporizer Volcano
Last edited by sassy; 08-22-2011 at 09:01 AM..
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01-22-2007, 05:52 AM
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#17
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Senior Member
Join Date: Sep 2005
Location: Philadelphia
Posts: 301
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Rhonda-
I had CET (cytoxan/epirubicin/taxotere) every 3 weeks for 4 cycles, then lump/SNB, and then 2 more cycles of it...
Regards,
__________________
Shell
init diag 3/17/03-stage IIIC
ER-/PR-/HER2+++
CET x4 neo-adjuvant
lump & SNB 8/03
CET x2
radiation and herceptin/navelbine 11-03-1/04
1st reoccur to lymph nodes 8/04
complete axillary dissection 12/04
herceptin/taxotere til progression (lungs) 3/05
xeloda w/out lapatinib trial 6/05
lapatinib/tykerb added 4/06
ended trial 8/06 due to progression
doxil / avastin 11/06-12/06 - wasn't working
navelbine/herceptin/avastin 12/06/3/07 - progression
gemzar/carboplatin/tykerb 4/07
mri shows extensive mets to bone in pelvic area 6/07
switched to abraxane (3 on/1 off) + tykerb 6/07
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01-22-2007, 11:18 AM
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#18
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Senior Member
Join Date: Jan 2006
Location: ALEXANDRIA, VA
Posts: 40
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Hi Rhonda,
My regiment has been as follows: 11/04 - 2/05 Taxol, carboplatin & hercp
every 3 weeks .... 3/05 - 5/05 hercp only every 3 weeks .... 6/05 - 12/05
hercp & navelbiene every other week ..... 12/05 - 9/06 hecp & navelbiene
every 3 weeks .... 9/06 to present day hercp only every 3 weeks .....
Take care & God Bless,
Debbie
__________________
dx stage 4 ... 11/04
3.2 cm mass breast & liver mets..
her2 +++ ; er- ; pr -;
11/04 treated with hercp, taxol & carboplatin - every 3 wks
3/05 ned - stopped chemo; hercp only
5/05 reoccurence left breast
6/05 added navelbiene w/ hercp every other wk
7/05 mascetomy
12/05 ned ; same regiment- every 3 wks
3/06 & 7/06 ned
9/06 stopped navelbiene.. hercp only.. every 3 wks;
10/06 pet scan shows positive lymph node in pec
12/06 PET no change;
4/07 scan showed 4 abnormal nodes in right pec area ... these have increased in activity since last scan... will start back on weekly navelbeine & hercp
7/07 PET done ..this time it showed new nodules in both right & left lung area as well as increased activity in pec area..
8/07 started Taxol & Carboplatin with Hercp every 3 wks
10/07 PET done ...Great Report ... NED ....
11/07 continue with Hercp every 3 wks & do Taxol & Carboplatin every 6 wks
4/09 still on same regiment; 1 positive node in left lung and right pec area
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01-22-2007, 02:54 PM
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#19
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Senior Member
Join Date: May 2006
Posts: 144
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I had DD AC, now finishing up a year of weekly Herceptin.
- Anna
__________________
- Anna
Stage I - DX 9/2005 ER/PR-, HER2+, grade 3, DCIS, IDC multi-focal (1.05cm)
DD 4 A/C finished Jan 31, 2006
Herceptin weekly finished Jan 31, 2007
recurrence to chest wall on last month of Herceptin
Stage 3B - 3/15/07 - 2 carcinomas in dermal lymphatic
Rads finished 6/5/07
12x TH finished 9/10/07
12/07 - Clear scan!
3/08 - 4 month Melatonin trial
1/09 - osteoperosis - start Alendronate
2/09 - 4-month Simivastin trial
3/13 - take drug holiday after 5 years of Alendronate
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01-22-2007, 04:26 PM
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#20
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Senior Member
Join Date: Jul 2006
Location: Southern California
Posts: 30
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Taxotere/Carboplatin/Herceptin - 3 weeks...dose dense not an option
__________________
Stage IIb, dx 12-26-05, age 37
Lumpectomy 1-4-06, 1.1 cm idc
3/19 pos. nodes (sentinel node was neg.)
ER +, PR +, Her2 +
TCH, radiation, Lupron/Aromasin
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