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11-15-2005, 10:55 AM
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#1
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Senior Member
Join Date: Sep 2005
Location: Central Massachusetts
Posts: 25
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Can Herceptin cause high blood pressure?
I did a search on the site, and didn't come up with anything directly - and I read the herceptin.com web site and saw nothing -
I have had 4 infusions of herceptin (1.9 years after finishing treatment for stage 2B). My blood pressure at my last infusion on Friday was really high and I just had it checked at work and it is still really high - especially for me since I have always run low... I have a call into my doctor, but wanted to ask -
Do any of you know if herceptin can cause hypertension?
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11-15-2005, 05:49 PM
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#2
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Sandy
It could cause high blood pressure, and also if it affects the heart it could cause the B/P to rise....also fluid retention...maybe a mild diuretic will bring it back down.....if not, a muga scan may be in order. I do know that mine is monitored every treatment. How high is it running above normal? Sounds like probably an easy fix, but one to take action on. You did the right thing by calling the Dr. If you are monitoring it on a B/P machine like at the drug store or Walmart...those aren't always the most accurate things...they get bumped etc. way too much to maintain true accuracy for a B/P that might need close monitoring. Let us know what you find out.
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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10-28-2006, 02:14 PM
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#3
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Senior Member
Join Date: Jun 2006
Location: Central North Carolina, USA
Posts: 112
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My blood pressure is also high
My blood pressure is also high. Before BC, my blood pressure was 110 over 70 at most. My last visit to the doc, my blood pressure was 150 over 75. My doctor said that it was not due to the herceptin. I am having a muga test on November 7. I have been on Herceptin since june of 2006. So almost 5 months.
__________________
DX 11/14/05, Stage 1C, Her2+ 3.4, ER+, PR+, K167 23%, Node Negative, MX0, Grade 3, 1.8CM, Lumpectomy 12/7/05; 6 rounds dense dose Taxol bi-weekly, 35 radiation, 1 year Herceptin, & Tamoxifen ongoing.
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10-28-2006, 05:06 PM
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#4
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Senior Member
Join Date: Feb 2005
Location: Norridgewock, Maine
Posts: 778
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My B/P ran high while on Herceptin. I never took anything for it. I also retained lots of fluid but not in my hands or feet only in the waist area. I have lost nearly 15 pounds since being off Herceptin for 2 1/2 months. I feel so much better!! My mugas always came out good. I will watch and see if it goes down. I have not been watching it but I will. hugs, Sandy
__________________
Dx. 03/01, Rt. IBC
AC/Taxatere
Rt. MRM-with graft Lt. simple
5 rads-skin mets
Herceptin, taxol, carboplatin (taxol seem to be the magic drug)
Navelbine & xeloda (did not work)
topical miltex for skin mets
Tykerb/xeloda
thoracentesis x 2 left lung fluid shows cancer cells
Port removal (4 years) with power port replacement
Doxil
Updated 05-07 Scans show no bone or organ involvement we shall see!
I shall not pass this way again. Any good I can do or any kindness that I can show let me not defer or neglect it for I shall not pass this way again.
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10-28-2006, 07:59 PM
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#5
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Senior Member
Join Date: Dec 2005
Location: Alexandria, VA
Posts: 1,055
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Mine has crept up 10 points top and bottom scores while doing H. I guess if you are over 140, it's time to talk to a cardiologist and get a script to bring it down. Best of luck. BB
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10-29-2006, 02:30 AM
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#6
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Senior Member
Join Date: Nov 2005
Location: Ireland
Posts: 3,463
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Me too!
My onc has just put me on meds for high blood pressure too and I'm almost finished my year of herceptin but never had a problem in the past as far as I know.
I don't know if it's the herceptin that caused it though,it was up all year during chemo and they thought it was just stress but had me wear a monitor for 24 hours at home to see and it did remain high even while sleeping.
Tricia
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11-08-2006, 01:59 PM
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#7
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Senior Member
Join Date: Jun 2006
Location: Central North Carolina, USA
Posts: 112
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Well, I had my second MUGA yesterday and my left ventricle ejection is 65%. That is actually an improvement over my last MUGA in December of 2005. My blood pressure was also lower than my last Herceptin treatment. I was worried because it was 150 over 75 3 weeks ago but yesterday it was 132 over 72.
__________________
DX 11/14/05, Stage 1C, Her2+ 3.4, ER+, PR+, K167 23%, Node Negative, MX0, Grade 3, 1.8CM, Lumpectomy 12/7/05; 6 rounds dense dose Taxol bi-weekly, 35 radiation, 1 year Herceptin, & Tamoxifen ongoing.
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