Hi Amazing Group,
I got this article today - it addresses the overweight woman and how leptin assists tumor growth. The link is below, but the gist of it I put in quotes below it. What I am wondering is for those of us who could stand to lose some weight (and lord knows I am trying - I had lost 30 lbs. when this started and steroids put most of it back on!) there are over the counter calcium chelation agents we could be taking. I would love some input on this! Anyone?
Fat Tissue-Derived Hormone Leptin Increases E-Cadherin Expression, Obesity-Breast Cancer Link Noted
http://www.medicalnewstoday.com/medi...=69362&nfid=al
"The results were the same in both. Combined exposure to leptin and estradiol increased tumor size, sometimes doubling it, and these changes correlated with an increase in E-cadherin.
Dr. Ando and his colleagues believe from their data that it is reasonable to suggest that the tumor suppressor E-cadherin may serve as a tumor enhancer when exposed to leptin and estradiol, that its ability to help cells aggregate then enhances the transformation of normal cells to cancerous cones, stimulating the growth of tumor mass.
When the researchers used an E-cadherin antibody or a
calcium-chelating agent to block E-cadherin function in the present of estradiol, this enhanced cell growth stopped."
Have a great day!
Donna
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