Question about FISH test

[Erin]

Hello Everyone,
I have been lurking for a few weeks reading posts and learning a lot. I am 50 years old and was dx 1/4/07 with RB DCIS and IDC, intermediate grade, stage 2. Er/Pr + HER2 +++

Had lumpectomy with sentinel node biopsy on 1/12/07. 3 of 3 nodes clean, one focally positive margin on the tumor due to its location against the chest wall. My HER2 status was confirmed using the FISH test, which came back 6.8. Will start 6 rounds of Taxotere/Carboplatin/Herceptin on 2/13, Herceptin to continue for 1 year. Rads and some kind of hormone therapy somewhere down the road.

Here is my question: Does the level of the FISH test have any relation to the relative agressiveness of the cancer? In other words, if your FISH comes back at 4.1 is that less agressive than 6.8? I know I need to ask my onc about it, but I will not see him again until next week. I was hoping one of you might have some info on it.

Thanks in advance for your help :-)