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		|  01-09-2007, 10:29 AM | #1 |  
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				Join Date: Oct 2005 
					Posts: 476
				 
		 
		 
		
		 
		
		
	
		
	
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				Joints ache probably Arimidex side effect
			 
 Dear Friends,
 I have been on Arimidex more than 15 months.  Lately, my joints (most of the right side) gave me sore and painful feeling, particularly when lying down.  If I had sufficient sleep, the discomfor is much less.  Do any of you have a similar problem?  If so, how did you remedy the problem?  Does a change to Femara help?  Thanks for answering.
 
				__________________Ann
 
 Stage 1 dx Sept 05
 ER/PR positive HER2 +++ Grade 3
 Invasive carcinoma 1 cm, no node involvement
 Mastec Sept 05
 Annual scans all negative, Oct 06
 Postmenopause. Arimidex only since Sept 06, bone or muscle ache after 3 month
 Off Arimidex, change to Femara 1/12-07, ache stopped
 Sept 07 all tests negative, pass 2 year mark
 Feb 08 continue doing well.
 Sep 09 four year NED still on Femara.
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		|  01-09-2007, 10:40 AM | #2 |  
	| Member 
				 
				Join Date: Dec 2006 Location: Millstadt, IL 
					Posts: 19
				 
		 
		 
		
		 
		
		
	
		
	
	 | Dear Ann,
 I started on Arimidex and had joint and bone pain so bad, could hardly walk.  I told my Onc and she started me on Femara.  I have been on Femara for 3 months and the pain is gone.  I also workout on an elliptical and this seems to really help your joints.  I do find that if I sit real long, it is hard to get up at first; your bones get really stiff.
 
 I have no side effects with Femara like I did with Arimidex.  Good luck with whatever you choose.
 
				__________________Linda2
 
 DX 6/2005
 Stage IIA, Grade I
 ER/PR +, HER2 +++
 Lumpectomy on Left breast 7/2005
 No lymph nodes involved
 4 cycles of A/C
 12 weekly doses Taxol and Herceptin
 33 Rads
 Herceptin for one year ended 12/2006
 Femara for 5 years
 NED as of now
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		|  01-09-2007, 11:59 AM | #3 |  
	| Senior Member 
				 
				Join Date: Aug 2006 
					Posts: 3,380
				 
		 
		 
		
		 
		
		
	
		
	
	 | Dear Ann,
 I started on Femara, and developed severe tinnitus within the first month. I had no joint pain. My onc switched me to Arimidex, to see if that would help. It took the tinnitus down a notch (it is related to estrogen deprivation, I believe, and Femara gets the levels down lower), however, on day 21 of Arimidex I noticed a sudden onset of joint pain and stiffness in the hands. These drugs definitely have side effects! It is a real case of "pick your poison." Good luck with your choice.
 
 Hopeful
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		|  01-09-2007, 04:36 PM | #4 |  
	| Senior Member 
				 
				Join Date: Oct 2005 
					Posts: 476
				 
		 
		 
		
		 
		
		
	
		
	
	 | Thanks for your answers.  Linda2, what do you mean by elliptical?  I guess the medication gives side effects varying with people.  We just have to try out the least offense medicine. 
				__________________Ann
 
 Stage 1 dx Sept 05
 ER/PR positive HER2 +++ Grade 3
 Invasive carcinoma 1 cm, no node involvement
 Mastec Sept 05
 Annual scans all negative, Oct 06
 Postmenopause. Arimidex only since Sept 06, bone or muscle ache after 3 month
 Off Arimidex, change to Femara 1/12-07, ache stopped
 Sept 07 all tests negative, pass 2 year mark
 Feb 08 continue doing well.
 Sep 09 four year NED still on Femara.
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		|  01-09-2007, 05:15 PM | #5 |  
	| Member 
				 
				Join Date: Dec 2006 Location: Millstadt, IL 
					Posts: 19
				 
		 
		 
		
		 
		
		
	
		
	
	 | An elliptical is sort of like a stair stepper and treadmill.  You can work your arms and legs.  
 I think you are right.  Everyone has different side effects from their medicine.
 
 Wish you the best.
 
				__________________Linda2
 
 DX 6/2005
 Stage IIA, Grade I
 ER/PR +, HER2 +++
 Lumpectomy on Left breast 7/2005
 No lymph nodes involved
 4 cycles of A/C
 12 weekly doses Taxol and Herceptin
 33 Rads
 Herceptin for one year ended 12/2006
 Femara for 5 years
 NED as of now
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		|  01-09-2007, 07:52 PM | #6 |  
	| Senior Member 
				 
				Join Date: Oct 2005 Location: New Jersey 
					Posts: 3,154
				 
		 
		 
		
		 
		
		
	
		
	
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				ONE YEAR on Arimidex....
			 
 Ann,had a great deal of bone and joint pain.  Esp. in the hip and hands.
 Was so stiff in the morning but exercise helped.  I also have an
 eiliptical exercise machine at home and it is a wonderful piece of
 euipment as it does not impact on the joints but allows you to have
 a great workout.
 
 I did stop taking the Arimidex after one year and now have been on
 Femara since Sept.  I am finding it much better and do not have
 the heavy joint pain.  But I do experience some mild ache and stiffness
 after sitting in the car for a period of an hour or more.  But once I
 move around it goes away.  I truly beleive that moving and exercise
 are very important while on either AI.  For me Femara seems to
 be better.
 
 Hope you feel better.
 Jean
 
				__________________Stage 1, Grade 1, 3/30/05
 Lumpectomy 4/15/05 - 6MM IDC
 Node Neg. (Sentinel node)
 ER+ 90% / PR-, Her2+++ by FISH
 Ki-67 40%
 Arimidex 5/05
 Radiation 32 trt, 5/30/05
 Oncotype DX test 4/17/06, 31% high risk
 TOPO 11 neg. 4/06
 Stopped Arimidex 5/06
 TCH 5/06, 6 treatments
 Herceptin 5/06 - for 1 yr.
 9/06 Completed chemo
 Started Femara Sept. 2006
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