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12-03-2006, 08:49 AM
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#1
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Senior Member
Join Date: Oct 2006
Location: Louisville KY
Naples FL
Posts: 665
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Herceptin Reaction???
First thanks for any information you can give me. I am on weekly Herceptin and had my third infusion last Tuesday with no problems at all. On this Saturday, I got a fever of 99.8, chills, and aches and I do not have the flue but it felt sort of like it. Today is Sunday and I am better but still ache. Is this any reaction anyone has had that long after an infusion? I am also doing radiation at the same time.
patb
Stage I, Grade 3, No Nodes, ER+ PR-, Her2positive, I had a lumpectomy in June and did chemo until October.
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12-03-2006, 08:54 AM
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#2
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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I experience a lot of bone/joint pain with Herceptin. At first it started out sort of like flu symptoms - general aching, etc. I have tried Herceptin every week and every three weeks trying to see if one would be better than the other. It doesn't matter what my schedule is I still have bone/joint pain and sometimes it is very severe. Herceptin has many side effects so all I can say is hang in there. There is a post on the board here titled "Herceptin side effects real or perceived." You might want to check that out. You can do a search and you will find the thread. Best of luck to you.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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12-03-2006, 09:30 AM
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#3
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Senior Member
Join Date: Sep 2006
Location: Savannah, Georgia
Posts: 301
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Herceptin
I started Hercptin in Sept. (this year) and did it weekly for the first eight tx's with absolutely no complaints. I really felt pretty good- even though I was on chemo through some of it. I got my first 3 week dose 2 weeks ago and have felt horrible ever since. Everything hurts- bones and joints, but especially having difficulties with muscular pain. Also have mild, but constant nausea. Don't know if this is the Herceptin , or if I had a bug. I guess that I'll need to try it again this week and see how I feel. If it doesn't change, I would rather take the weekly dose and feel better even though its a little more hassle.
Kelly
__________________
dx'd 05/06, 37 years old
er/pr-, Her2+, grade 3
double mastectomy, immediate reconstruction- implants
Stage 2b, 2 tumors- 2.2 cm and 0.6 cm, 3/5 + nodes
all scans clear
genetic testing- negative
06/06 began dd A/C x 4, 12 weekly Taxols w/ Herceptin
30 rads
Herceptin weekly x 1 year
Herceptin completed 08/07
Port removed 12/26/07 MERRY CHRISTMAS!!!!!!
05/17/08 Two year anniversary NED
"We gain strength, courage, and confidence by each experience in which we really stop to look fear in the face... you must do the thing that you think you cannot do."
-Eleanor Roosevelt
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12-03-2006, 09:35 AM
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#4
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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I think that Herceptin must have a cumulative effect. When I first started I had no problems and now with each treatment I get the bone/joint/muscle pain increases. I guess it's a small price to say to stay NED.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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