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Old 06-26-2006, 11:49 AM   #1
StephN
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Question Breast size changes??

Hi everyone -
Susan W in another thread mentioned her breasts getting larger prior to her diagnosis. Al then commented that additional estrogen going to this area may be a troublemaker.

My breasts grew from 34b to 36c just before menopause and I always wondered if this had anything to do with getting cancer. I am er/pr negative, but that does not mean that hormones were not involved. Diagnosis was about 9-10 months into menopause.

I am wondering how many of us here had noticeable change in breast size to the point of having to get all new bras, and clothes getting too tight. OR a reduction from weight loss.
I have not taken the time to look up any research in this direction, but would hope some exists.
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Live in the moment.

MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.

Last edited by StephN; 06-26-2006 at 12:47 PM..
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Old 06-26-2006, 12:35 PM   #2
RhondaH
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Prior to having Tony I was a 40D...

AFTER having him I became a 40G (thought it was due to nursing him for a year), but they never went back until after dx and I lost 40 lbs.

Rhonda
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Dx 2/1/05, Stage 1, 0 nodes, Grade 3, ER/PR-, HER2+ (3.16 Fish)
2/7/05, Partial Mastectomy
5/18/05 Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan)
8/1/05 Finished 33 rads
8/18/05 Started Herceptin, every 3 weeks for a year (last one 8/10/06)

2/1/13...8 year Cancerversary and I am "perfect" (at least where cancer is concerned;)


" And in the end, it's not the years in your life that count. It's the life in your years."- Abraham Lincoln
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Old 06-26-2006, 02:25 PM   #3
astrid
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Over the years. I went from a 32C to a 36D. I am still a 36D. This was not all related to pregnancy. I was 92 pounds when I first got married and was 138 when I was diagnosed. I am now 123. I have also wondered if the rapid breast growth was a sign. I had people ask me if I had implants. I have a strong family history and I am a DES baby. So I tend to think my cancer was caused by genetics or DES. I tested negative for BRCAs
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Old 06-26-2006, 02:44 PM   #4
IRENE FROM TAMPA
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Glad you brought it up...

since that is what happened to me upon my detection in 1996.

I noticed that bra on my left side was becoming tighter. Stupid me never even thought of anything being wrong, little alone cancer. I had no pain, felt no lumps, nothing other then becoming larger and since that side was always a bit larger, I thought nothing of it. I was due to have my mamo in a few months anyway. Well it's a good thing I did, since that is when it was found- Infiltrating Ductal Carcinoma.

I am also Er/Pr negative and I was 50 when diagnosed. Had not gone into menopause yet.

I was passed on this web site for IBC which I never heard of myself either.

Take a moment and watch the video. It's an eye opener for yet another type of cancer.

ww3.komotv.com/global/video/popup/pop_player.asp?

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1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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Old 06-26-2006, 02:48 PM   #5
IRENE FROM TAMPA
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Sorry Steph

Sorry Steph

I just noticed that you had already posted that video site. Well I guess twice the info can't really hurt none.
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Irene from Tampa
1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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Old 06-26-2006, 04:50 PM   #6
Sandy H
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This is an interesting question Steph brought up. I was a 36b then went to 36c and at diagnose I was a 38DD! I was 54 years old when diagnosed with IBC. People were beginning to tell me I was beginning to look like Dolly Parton! When I went for my fitting after mastectomies they told me I should stay with what I was before surgery. I said, "no way" when I told her what size I was she couldn't believe it. Now, at least I can choose the size I want to be. hugs, Sandy
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Old 06-27-2006, 10:49 AM   #7
panicked911
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breast size chnages

before turing 40 and even after 2 kids and breats feed ing for a year I was a 32B. Somewhere right around 40 I grew hips and my chest swelled to a 34 C for 2.5 weeks during the month and 34D the week before zi was getting my period. I "complianed" to the ob/gyn who said only you gain in the chest and hips - noone ever took it seriously ..
AT 43 I was diagnosised with stage 1 two peas and pencil point -
when my surgeon looked at the pathology report she said that the tumors were there b/w 3-5 years - almost to the point when i noticed the chnage in my chest.
Directly following surgery I started tamoxifen and within 2 weeks noticed my chest was shrinking - e-mail surgeon who said she knew it would work but did not think that fast - I was then switched to arimidex and lupron and started with Herceptain -wouldn't you know it - gained 10 pounds and my chest is back to where it was pre arimidex but withnone of the pain and swelling I used to get. Had an MRI in may which showed everything was fine - time will tell I guess.

Susanne
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Old 06-27-2006, 01:21 PM   #8
Patty H
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I never made the connection before. But yes I went from a 34b to a 36c, probably in the last year before I was dx. I had commented to my friends that this was one nice thing about getting older. I wasn't in menopause yet, I was 50 and near it. I figured it was because my weight was up to 127. The most I had weighed unpregnant. I was also er nagitive. Patty H
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Old 06-27-2006, 10:41 PM   #9
al from Canada
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maybe

Now that I think of it, Linda did blossom but, don't most ladies between 45 - 55? This could be a red herring as metabolism does change. Guys experience similar things (except me).
Suzanne, this 3 - 5 year number is also a red herring as oncs don't have a fraction of the answers about HER2 disease. They are basing their guestimates on HER2 negative stats. From experience I can tell you this, an aggressive HER2 cancer can double in size in a few months. Al
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Old 06-28-2006, 06:58 AM   #10
panicked911
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breast changes

Al:

You are absolutely right for the "typical" her2 tumor that is er- pr- or weakly positive. I am told my my onc an surgeon at Memorial Sloan Kettering that when you are a strong triple positive ( which I am) those guidelines on rate of growth get skewed - hence the 3 -5 year estimate from the surgeon. Also skewing the numbers is th fact that not only strongly triple positive I also had three tumors growing right next to each other independant ( the smaller may have been a focal - not sure because it was so small .1 mm)

I could not have had better care than where I was treated botht he onc and the surgeon are very well regarded and have are top researchers in their repsected fields. Yet neither had ever seen anything quite like this - hence my searching for answers and finding this sight -which has been wonderful.
But interestingly I can pin point the changes in my breasts corrolating back the 5 years and in the past three before diagnosis was particularly bothersome and I was not menapausal and in excellent physical shape so weight wasn't the reason for the changes.

Interestingly I asked the onc about the increase and chnages in breats size prior to diagnosis and she said she has heard it before but obody has ever done " a study" There was a study out of Harvard that suggested women with smaller frames ( 32, 34) and cup size C and larger were at an increased risk for developing breast cancer. Go figure.

Susanne
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