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Old 03-02-2008, 05:40 PM   #1
Kasey
Junior Member
 
Join Date: Mar 2008
Posts: 3
Ixabepilone---Ixempra

Hi,

I usually post on a different board but somebody suggested I post here for more information. After two battles with breast cancer (opposite breasts) I was diagnosed with stage IV breast cancer in February 2007. Since then I have been on Gemzar/Herceptin, Xeloda/Tykerb, and Navelbine/Herceptin. I have had progression on each one. My Onc has suggested Ixempra next and I was hoping to get some information on side effects and can't seem to find much info about it. Can anyone tell me if you had nausea, hair loss, ect? And how about pre meds? Did you need to take anti-nausea drugs afterwards? Thank for any info you can share.


Kasey

er, pr neg, Her2 pos
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Old 03-02-2008, 06:40 PM   #2
LOPSIDED
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Join Date: Apr 2006
Location: FLORIDA
Posts: 148
I Started Ixempra The Middle Of December. I Do Get Pre-meds Before Treatment. I Also Get Shots To Boost White Blood Cells The Following 2 Days After Chemo. I Do Usually Throw Up Once Or Twice The Third Day Following Chemo. I Am Very Tired And Seem To Be Getting Weaker With Each Treatment. My Red Cells & Hemoglobin Are Low. I Am Going To Ask My Doctor If They Can Give Me A Shot To Boost My Red Cells. I Am Going To Do 6 Treatments Of Ixempra & Then Start Tykerb. I Did Go For Scans After 3 Treatments And It Showed A 50% Reduction In My Enlarged Lymph Nodes. They Told Me I Might Not Lose My Hair, But It Started Falling Out 10 Days After First Treatment. I Just Have Two More Treatments To Go & Off To Another Ct Scan. Will Keep You Posted.
__________________
SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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Old 03-02-2008, 10:10 PM   #3
smith
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Join Date: Jan 2008
Posts: 3
I have been on Ixempra plus Tykerb since January. I have not had any nausea due to the chemo. And I did not lose my hair. My white counts have been fine, but my red counts do drop. I am very tired. Usually on day 2 I can barely get out of bed, but then each day I get a little better. I also have body aches. The aches have gotten better with each treatment, the tiredness has not. I really only stay in bed 1 day. All in all this has not been a bad chemo. No more trips to malls or hiking. I had a scan after 2 treatments and am stable. I hope my next scan shows shrinkage. But for now I will take stable.
__________________
  • diagnoised 4/01 stage 2, 7 out of 21 lymph nodes pos. ER/PR+, her2+. AC/Taxotere 35 rads. Tamoxifen, Arimidex, lupron.
  • mets to liver 4/03 Navelbine/Herceptin, RFA to liver. NED til 05.
  • mets to femor 5/05. Rads, Zometa.
  • mets returned to liver 10/05. RFA to femor and liver 3/06 after hormone treatments failed. Biopsy showed now ER/PR-. Xeloda/Zometa.
  • mets returned to liver 12/06 Xeloda/Tykerb/Zometa NED for 2 months.
  • mets returned to liver 8/07. Chemo bead embolism to largest of 3 tumors. Day of RFA CT showed 3 tumors had turned into 30+. Gemszar/Herceptin/Zometa.
  • Failed, now on Ixempra/Tykerb/Zometa
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Old 03-03-2008, 01:50 PM   #4
Kasey
Junior Member
 
Join Date: Mar 2008
Posts: 3
Thank you Sheila and Smith for the info. That is weird that one of you lost your hair and one did not. Wonder what determines that? I'm not sure if I should order a wig or not??

Sheila, I'm glad to hear about your reduction! And Smith, stable is good too! I'd love to hear either!

Thanks again,
Kasey
__________________
1999-bc in right breast, a/t(taxotere), rads, triple neg
2005-bc in left breast, c/t(taxotere), triple neg
2007-stage IV, er,pr neg, her2 pos, have done Gemzar/Herceptin, Xeloda/Tykerb, Navelbine/Hercepin. Progression each time
Mets in chest nodes, liver, lungs
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