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12-01-2010, 11:24 AM
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#1
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Senior Member
Join Date: Nov 2004
Posts: 190
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New Treatment plan
When I last reported, I had just failed TDM1 with a soft tissue met in the chest, sternum, and possible liver mets. I got some great suggestions.
Lori, the Queen of Cryo, suggested freezing the liver mets. The cryo guys looked at my scans (ct) and said that they didn't think I had liver mets. A pet/ct a week later proved they were right!
So I found a rad on who says she can zap the chest area and I should start next week.
The goal is to become NED so that I can qualify for a vaccine trial at hopkins. I don't know if anyone on this site is in that trial (if so pm me), but when I get in I will definitely tell you guys all about it
So I would like to personally thank Barbara H because I am now on Tykerb and Herceptin, Lori R who introduced me to Cryotherapy and Darlene Denise who suggested rads to the chest area.
Kim
__________________
8/98 dx right breast
5/2003 tram flap right breast
8/2004 dx new primary left breast with inflammatory bc
er/pr-, her2neu+++
8/19 taxotere and herceptin
1/15/2005 Navelbine/Herceptin
4/2005 radiation and Herceptin
5/15/2005 Herceptin alone
2/12/2008 skin biopsy positive
2/14/2008 met to sternum, possibly right breast
2/27/08 Start omitarg, herceptin, taxotere trial
3/17/08 Kicked off trial because I started too close to my last herceptin
3/19 start tykerb xeloda
Right breast confirmed met
5/15/08 skin mets gone, no hypermetabolic activity in breast, sternum healing
8/24/08 scans still look good. sternum still active with scarring. No evidence of progression
10/08 Progression in sternum
12/08 Start TDM1 trial
1/09 Scans show stable
12/09 1 year on TDM1 still stable
10/10 progression in chest and liver
11/10 false positive of liver mets; tykerb and herceptin
4/11 Tykerb/Herceptin/Xgeva
4/11 Rads to Sternum
5/12/12 NED Herceptin/Zometa
3/16/19 still NED Herceptin/Zometa very 6months
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12-01-2010, 01:34 PM
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#2
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Senior Member
Join Date: Feb 2007
Location: Paris, France
Posts: 858
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Re: New Treatment plan
Hi Kim. I was so sorry the TDM1 did not work better but the fact that there are no liver mets is a relief. The plan seems good and I hope you can qualify for the trial soon once you will have zapped away the %/!§$£!z! chest met. Michka
__________________
08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex
12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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12-01-2010, 05:34 PM
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#3
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Re: New Treatment plan
Hi Kim,
I hope that Tykerb and Herceptin is a good combination for you. I have been on it for over a year now and it is still working. My thoughts are with you.
Kind regards,
Barbara
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12-02-2010, 09:58 AM
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#4
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Senior Member
Join Date: May 2010
Location: Ireland
Posts: 271
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Re: New Treatment plan
Hi Kim,
What does a 'soft tissue met to the chest' mean? Is it visible like a skin met?
__________________
Delaney, dx 2008 lumpectomy,mastectomy,a/c,paxitaxol, tyverb 1 yr.
dx 2010 mets lymph nodes, skin, lung. start taxotere/herceptin.
Stopped taxtere/herceptin, now on tyverb/xeloda.
Lung mets shrinking.
Back on Herceptin with T/X. Partial response.
Skin mets progressing. Radiation scheduled mid february 2011.
Spot found on hip - radiation to hip beginning mid February 2011.
Now trying Gemzar/Tyverb/Herceptin and Zometa.
CT scan Feb 2011 - lung clear!
Brain mets (specks) - radiation mid Feb.
Brain Scan June'11 - Clear
CT Scan June'11 - Good - skin met active - watch and wait.
Surgery to remove skin met. Surgery to back 2012, four titanium rods inserted. Skin mets reappear. On Navelbine, not working. 4 week washout, start Myocet for skin and lung mets August 2012. Brain scan clear despte intermittent blurry vision (something hiding? Am suspicious but hopeful. )On we go, glad to be here.
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12-02-2010, 10:55 AM
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#5
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Senior Member
Join Date: May 2006
Posts: 3,142
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Re: New Treatment plan
I have my fingers crossed for you. I hope Herceptin and Tykerb works its magic. Have a great holiday season.
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12-02-2010, 02:25 PM
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#6
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Senior Member
Join Date: Nov 2004
Posts: 190
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Re: New Treatment plan
Hi Delaney,
My soft tissue met is in my reconstructed breast, not visible, just underneath the skin. I have had skin mets before but tykerb/xeloda cleared them up.
__________________
8/98 dx right breast
5/2003 tram flap right breast
8/2004 dx new primary left breast with inflammatory bc
er/pr-, her2neu+++
8/19 taxotere and herceptin
1/15/2005 Navelbine/Herceptin
4/2005 radiation and Herceptin
5/15/2005 Herceptin alone
2/12/2008 skin biopsy positive
2/14/2008 met to sternum, possibly right breast
2/27/08 Start omitarg, herceptin, taxotere trial
3/17/08 Kicked off trial because I started too close to my last herceptin
3/19 start tykerb xeloda
Right breast confirmed met
5/15/08 skin mets gone, no hypermetabolic activity in breast, sternum healing
8/24/08 scans still look good. sternum still active with scarring. No evidence of progression
10/08 Progression in sternum
12/08 Start TDM1 trial
1/09 Scans show stable
12/09 1 year on TDM1 still stable
10/10 progression in chest and liver
11/10 false positive of liver mets; tykerb and herceptin
4/11 Tykerb/Herceptin/Xgeva
4/11 Rads to Sternum
5/12/12 NED Herceptin/Zometa
3/16/19 still NED Herceptin/Zometa very 6months
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12-03-2010, 04:53 AM
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#7
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Senior Member
Join Date: Feb 2009
Posts: 1,526
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Re: New Treatment plan
Hi Kim
Glad you are moving forward again.
Please could you tell me which trial you are meaning?
many thanks
Ellie
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