Re: Protocol Question: every 7 or 21 days?
There were so many different Herceptin studies for both adjuvant and metastatic use. Some studies used the weekly regime and others used the triple dose - every 3 week regime.
It depends but many women get the first doses weekly along with weekly Taxol or Taxotere (12 doses). After that, they are switched to the triple dose and only have to come every 3 weeks (gives some freedom). However, I have heard (this may not be factual) that women who may have a potential for heart problems take the weekly as you get less drug. Also, allergic reactions might be less with the weekly due to less drug.
However, in general, there is no difference between the two treatment protocols except for the time factor for the patient.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
|