for Stage IV--if at first you do not succeed (with herceptin combo), try try again!!

[Lani]

It seems that the time to progression with the first herceptin based combination therapy given after becoming Stage IV predicts how long one would take to progress on the second herceptin based combo therapy.

Another argument backing "herceptin beyond progression" to use with governments, insurance companies who want to stop herceptin once progression occurs and "throw the baby out with the bathwater"

Herceptin, for now, seems to be the framework upon which other agents are added to achieve the longest possible times to progression. Lapatinib, for now, seems perhaps best added to herceptin rather than replacing it.

All these "for nows" just means until more data comes in from other studies.