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Old 10-02-2014, 05:08 PM   #1
sassy
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Join Date: Sep 2005
Location: Mountains of Virginia
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FW: Nuanced discussion on the management of HER2-positive breast cancer

From: Research To Practice [mailto:education@researchtopractice.com]
Sent: Saturday, September 27, 2014 7:00





Proceedings from a satellite symposium held in Chicago (June 2, 2014). Faculty, from left: Fabrice André, MD, PhD, Edith A Perez, MD, Harold J Burstein, MD, PhD, Kimberly L Blackwell, MD and Mark D Pegram, MD.

Breast cancer is undoubtedly the highest-profile and most popular topic in contemporary cancer medicine, and research investment in this disease far outpaces even its closest oncologic competitors. Because of this, a plethora of new information is constantly emerging, helping to improve our collective understanding and to refine state-of-the-art disease management. Interestingly, despite the fact that more than 60% of all breast cancer patients present with hormone-sensitive disease, it seems as if almost every month we are faced with a new critical data set that affects the care of the 20% or so with HER2-driven breast cancer.

Watch proceedings from the event
To explore the most significant recent therapeutic advances in this important patient subset and document how this information has helped to refine current treatment and ongoing research, we recently hosted a specially designed satellite symposium. Prior to the meeting, we consulted with 5 general medical oncologists to identify actual cases from their practices in which new research data contributed to their clinical decision-making for patients with early and advanced HER2-positive breast cancer. At the meeting, we invited each of our renowned faculty members to discuss how they would have approached these clinical situations and to informally comment from the podium on key related recent publications. The result was a dynamic and engaging symposium that provided in-depth and thoughtful perspectives on the nuanced management of HER2-positive disease.

As is always the case, only a small fraction of our national and international audience was actually on hand in Chicago, so to make this content available to everyone we are now posting the virtual video proceedings, along with all of the slides presented at the event.

Neil Love, MD
Research To Practice
Miami, Florida




Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Research To Practice designates this enduring material for a maximum of 2.25 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity is supported by an educational grant from Genentech BioOncology.



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Rhonda (Sassy)
dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
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NED and no meds.......
14YEARS NED!
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