HER2 Support Group Forums - View Single Post - Kadcydla versus neurosurgery and paralysis

dchips1 · 12-26-2013, 05:45 PM

Does Kaycylda cross the blood brain barrier?
I am really in between a rock and a fast moving glacier. Neurosurgeon wants to do a laminectomy style removal of the t-8-9 lesion he says it shifts enough to right, gave oncologist info on IT Topotecan, has not found anyone using for "breast cancer mets" So the insurance will pay for it. He suggegeted KAdcyla, what I have found is that it sometimes they used in place of Tykerb and xeloda in a couple of trials. I am still on Tykerb but not xeloda anymore.

I have not a lot of time with the nerve symptoms, getting worse. Nor to reinvent the wheel .

Thanks Darita Pfeister

12-26-2013, 05:45 PM	#1
dchips1 Senior Member Join Date: May 2006 Location: Mesa, Az Posts: 219	Kadcydla versus neurosurgery and paralysis Does Kaycylda cross the blood brain barrier? I am really in between a rock and a fast moving glacier. Neurosurgeon wants to do a laminectomy style removal of the t-8-9 lesion he says it shifts enough to right, gave oncologist info on IT Topotecan, has not found anyone using for "breast cancer mets" So the insurance will pay for it. He suggegeted KAdcyla, what I have found is that it sometimes they used in place of Tykerb and xeloda in a couple of trials. I am still on Tykerb but not xeloda anymore. I have not a lot of time with the nerve symptoms, getting worse. Nor to reinvent the wheel . Thanks Darita Pfeister __________________ dx 1/06 IDC 2cm 38 at dx 2/06 L mast nodes 3/9+ SNB neg ER-/Pr - her2 + Stg 4 liver/pelvis 3/06-9/06Taxol/Carbo/zometa/Herceptin 3/07 6 brain mets WBR down to c-2 4/07 osteonecrosis jaw 1/08 mri new 9mm lesion right lower side 2/08 gamma knife 1 lesion 11/08 regamma 10/09 latent rad necrosis to brain met, 1/20/10 crani: lesion necrosis w active cells continue her add tykerb 1/11 NED just Ingrown toenail! YEAH GOD 8/11 Tykerb, herceptin weekly, elevated her2 levels, negative scans oct -march 11 new neuro deficits lower legs 3/12 2 spinal metsTykerb, Herceptin 04/12 4050cGY rads T 2-4 & T7-9 5/12 Brain,cervical lumbar clear/thoracic slight decrease 10/12 t 2-4 shrunk t-9 grew start Xeloda, 02/13 stop xeloda,5/13 on metformin, decadron, Tykerb, iv and IT herceptin 5/30/13 total #11 #2 of 80mg dose weekly. 9/13 100mg of IT her, IV hern, 750 mg tykerb, 3mg dec. last Mri T--3 SHRUNK t7-9 shrunk no edema. Left shift in CBC bone marrow BX negative. 10/13 Ct has shown Double left ureters with stones/cysts in them, after 3 births and lots and U/S iit takes cancer to figure out you have 2 smaller ureters going into 1 kidney! 12/13 Mri brain no new lesions, cervical and lumbar arthritis. Tspine lesion at T3 stable, T 7-9 GROWTH lots of pain 1/29/14 HIHO HIHO its off to Neuro surgery I go Life is Good when you wake up in the morning and take a breath and know that God has given me another day.