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Old 11-18-2014, 08:44 AM   #1
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'lizbeth's Avatar
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
Post While we wait on information for the Neuvax Her2 3+ trial . . .

a reminder that there is one for the lower expressors that is currently enrolling.

If you know of anyone who is newly diagnosed as a "triple negative" or 'Her2 negative" PLEASE share about this trial and encourage them to look into it. The interim data has been very promising and participants have had the good fortune of remaining cancer free in the vaccine arm for 48 months.

So think of anyone who you know in the community, support groups, church, school, etc and let them know to look into this vaccine.

Experimental: Herceptin + NeuVax vaccine
Patients randomized to this arm will receive Herceptin every 3 weeks as monotherapy for 1 year. The first Herceptin infusion will be given no sooner than 3 weeks and no later than 12 weeks after completion of standard of care chemotherapy/radiotherapy. Herceptin will be dosed at the recommended initial loading dose of 8 mg/kg and at recommended maintenance doses of 6 mg/kg q3wk. Patients will receive vaccinations of NeuVax vaccine (E75 peptide 1000mcg + GM-CSF 250mcg) administered intradermally every 3 weeks for 6 total vaccinations, 30-120 minutes after completion of Herceptin infusion. The NeuVax vaccine series will begin immediately after completion of the third Herceptin infusion. Patients will be blinded as to whether they are receiving NeuVax vaccine or GM-CSF. After completion of primary vaccine series, patients will receive four NeuVax vaccine booster inoculations to be administered at 12, 18, 24, and 30 months from date of first Herceptin infusion.
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes

Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"

Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla

Reconstruction: TRAM flap, partial loss, Revision

The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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