HER2 Support Group Forums - View Single Post - CEP17 seems to predict anthracycline benefit

Christine MH-UK · 03-27-2010, 08:14 AM

It is on the same chromosome as Her2, but different.

Key points according to blurb:
* CEP17 BC survival improves by 2/3rds with addition of anthracycline
* Suggests that CEP17 mutation can be told from the FISH test
* Suggests that only CEP17 BC benefits from anthracyclines.

http://www.nlm.nih.gov/medlineplus/n...ory_96884.html

As someone who got neoadjuvant anthracyclines and suffered greatly without having an enduring response, I think that this is great news.

03-27-2010, 08:14 AM	#1
Christine MH-UK Senior Member Join Date: Sep 2005 Posts: 414	CEP17 seems to predict anthracycline benefit It is on the same chromosome as Her2, but different. Key points according to blurb: * CEP17 BC survival improves by 2/3rds with addition of anthracycline * Suggests that CEP17 mutation can be told from the FISH test * Suggests that only CEP17 BC benefits from anthracyclines. http://www.nlm.nih.gov/medlineplus/n...ory_96884.html As someone who got neoadjuvant anthracyclines and suffered greatly without having an enduring response, I think that this is great news.