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Old 11-11-2015, 02:28 AM   #16
agness
Senior Member
 
Join Date: Aug 2014
Location: Seattle, WA
Posts: 285
Re: Progesterone Positive, Estrogen Negative

Was your tumor tissue ever tested by Foundation One or anyone else? Did you have Mammaprint or other testing done? There might be more to understand about your unique mutation.

I looked into this a bit as PR+ was deemed to be an anomaly in most places I looked. I did see that it can be related to one not metabolizing progesterone well and having a build-up of unfavorable levels of progesterone metabolites in the body.

Having had experience with uterine fibroids in the past and studying the premises of John Lee about using natural progesterone during perimenopause sort of started my understanding but as I learned about fibroids I read that sometime progesterone causes them to grow and not just excess estrogens.

I think there is more to understand about why the body doesn't process progesterone well.
__________________
  • Dx 2/14 3b HER2+/HR- left breast, left axilla, internal mammary node (behind breast bone). Neoadjuvant TCHP 3/14-7/2. PCR 8/14 LX and SND. 10/21-12/9 Proton therapy to chest wall.
  • Dx 7/20/15 cerebellar met 3.5x5cm HER2+/HR-/GATA3+ 7/23/15 Craniotomy.
  • 7/29/15 bone scan clear. 8/3/15 PET clean scan. LINAC SRS (5 fractions) Sept 2015. 9/17/15 CSF NED, 9/24/15 CSF NED, 11/2/15 CSF NED.
  • 10/27/15 atypical uptake in right cerebellum - inflammation?
  • 12/1/15 Leptomeningeal dx. Starting IT Herceptin.
  • 1/16 - 16 fractions of tomotherapy to cerebellum, break of IT Herceptin during rads, resume at 100 mg weekly
  • 3/2016 - stable scan
  • 5/2016 stable scan
  • 7/2016 pseudoprogression?
  • 9/2016 more LM, start new chemo protocol and IV therapy treatment with HBOT
  • 11/2016 Cyberknife to temporal lobe, HBOT just prior
  • 12/2016 - lesions starting to show shrinkage
  • 8/2017 - Stable since Dec 2016. Temporal lobe lesion gone.
  • Using TCM, naturopathic oncology, physical therapy, chiro, massage, medical qigong, and energetic healing modalities in tandem. Stops at nothing.
  • Mother of 2 boys - ages 7 and 10 (8/2017) and a lovely partner with lots to live for.

Last edited by agness; 11-11-2015 at 02:30 AM.. Reason: Typo
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