HER2 Support Group Forums - View Single Post - My Opinion of the Biggest Highlights of SABCS

Becky · 12-20-2006, 08:11 AM

I wanted to add another thing that came up about the TanDem trial (Arimidex vs Arimidex + Herceptin). Dr. Hudis made a statement in regard to the great results of this trial and then (correlated) this to the adjuvant Herceptin trials.

His thoughts? - what are the response rates with or without hormonal therapy. Which hormonal therapy - ie : Tamoxifen, AI - which AIs. His view is that some of the benefit % out of the adjuvant trials comes from combining Herceptin with hormonal therapy and the fact that women who are also hormone positive have less aggressive disease (in theory).

Just another thing to discuss on the board.

12-20-2006, 08:11 AM	#10
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	I wanted to add another thing that came up about the TanDem trial (Arimidex vs Arimidex + Herceptin). Dr. Hudis made a statement in regard to the great results of this trial and then (correlated) this to the adjuvant Herceptin trials. His thoughts? - what are the response rates with or without hormonal therapy. Which hormonal therapy - ie : Tamoxifen, AI - which AIs. His view is that some of the benefit % out of the adjuvant trials comes from combining Herceptin with hormonal therapy and the fact that women who are also hormone positive have less aggressive disease (in theory). Just another thing to discuss on the board. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"