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Re: any tumor tests to predict which chemos work better?
I have been following this thread with interest.
I live in Australia and currently have tumor tissue from my initial surgery being tested. It is being tested by a government laboratory and the testing is in R&D phase - I understand that initial testing is chemosentivity of which we have preliminary results after a few months. The additional testing is various types of assays?
I have to admit to finding the above discussion confusing - can anyone explain perhaps in more lay terms the types of testing.
I tried to get samples of the lung mets this week with biopsy but was only able to get 2 cores and that was only enough for the lab to do the standard tests - we may get a bit of tissue for the R&D testing. The pathologist working on my tissue talks about developing testing for individualised cancer treatments. The reason I am so interesting is I went from a stage 2b to stage 4 while receiving, FEC, Taxotere and Herceptin. Quite obviously FEC was completely useless in fighting the cells in my bloodstream and so far Herceptin has done little either.
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Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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