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Nguyen · 04-24-2021, 10:10 PM

You didn't list ER/PR and no endocrine treatment, so you are ER/PR negative? When was the Foundation One (F1) analysis done? Was the F1 report indicate how strong is ERBB2 amplification? From F1 report, for each of those mutation was there a list of possible treatment? Is there a section (in F1 report) label mutation of unknown significant? Is there a tumor marker (Ca27.29) history? Progression is confirmed by imaging?

When you wrote "just lung", did they image the entire body including brain?
Off the top of my head, ask your oncologist about Margetuximab or DS8201 (trade name Enhertu or Trastuzumab Deruxtecan).

04-24-2021, 10:10 PM	#8
Nguyen Senior Member Join Date: Nov 2005 Posts: 515	Re: Looks like I have progression You didn't list ER/PR and no endocrine treatment, so you are ER/PR negative? When was the Foundation One (F1) analysis done? Was the F1 report indicate how strong is ERBB2 amplification? From F1 report, for each of those mutation was there a list of possible treatment? Is there a section (in F1 report) label mutation of unknown significant? Is there a tumor marker (Ca27.29) history? Progression is confirmed by imaging? When you wrote "just lung", did they image the entire body including brain? Off the top of my head, ask your oncologist about Margetuximab or DS8201 (trade name Enhertu or Trastuzumab Deruxtecan).