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valleygirl · 04-24-2021, 05:15 PM

From my foundation one: ERBB2 amplification, CDKN2A/B loss, MLL3 Q1211, TP53 R248Q. First diagnosed in 2011 stage 3C did AC/taxol followed by a year of Herceptin. 2015 diagnosed stage 4 mets to lungs, started taxotere with Herceptin and perjecta. Had
progression in 2016 started NCT0303217 at Dana Farber TDM1/Keytruda. Progression in AUG.2018 started NCT02614794 at UPENN Xeloda, Herceptin and Tucatinib. Progression last week, still just lungs.

04-24-2021, 05:15 PM	#7
valleygirl Senior Member Join Date: Jan 2012 Location: Millsboro, Delaware Posts: 140	Re: Looks like I have progression From my foundation one: ERBB2 amplification, CDKN2A/B loss, MLL3 Q1211, TP53 R248Q. First diagnosed in 2011 stage 3C did AC/taxol followed by a year of Herceptin. 2015 diagnosed stage 4 mets to lungs, started taxotere with Herceptin and perjecta. Had progression in 2016 started NCT0303217 at Dana Farber TDM1/Keytruda. Progression in AUG.2018 started NCT02614794 at UPENN Xeloda, Herceptin and Tucatinib. Progression last week, still just lungs. __________________